Curcumin and Resveratrol in the Management of Cognitive Disorders: What Is the Clinical Evidence?
In this review, the published clinical trials investigating curcumin and resveratrol in the prevention or treatment of cognitive disorders are analyzed and the results are disappointing and do not allow to draw conclusions about the therapeutic or neuroprotective potential of these compounds.
A Polyphenol Rich Extract from Solanum melongena L. DR2 Peel Exhibits Antioxidant Properties and Anti-Herpes Simplex Virus Type 1 Activity In Vitro
The results suggest the DR2B and DR2C extract as a promising new anti-HSV-1 agent, which partly counteracted the tBOOH-induced cytotoxicity, with a remarkable lowering of lactate metabolism under both normoxia and hypoxia.
Chemoresistance and chemosensitization in cholangiocarcinoma.
Antiviral and Antioxidant Activity of a Hydroalcoholic Extract from Humulus lupulus L.
- A. Di Sotto, Paola Checconi, L. Nencioni
- BiologyOxidative Medicine and Cellular Longevity
- 24 July 2018
It is found that HOP extract significantly inhibited replication of various viral strains, at different time from infection, and inhibited lipoperoxidation and the tBOOH-induced cytotoxicity.
Genotoxicity assessment of some cosmetic and food additives.
Sisymbrium Officinale (L.) Scop. and its Polyphenolic Fractions Inhibit the Mutagenicity of Tert‐Butylhydroperoxide in Escherichia Coli WP2uvrAR Strain
- A. Di Sotto, S. Di Giacomo, C. Toniolo, M. Nicoletti, G. Mazzanti
- Medicine, ChemistryPhytotherapy Research
- 1 May 2016
Results can support the traditional use of hedge mustard by smokers to restore the vocal cord function affected by the oxidative damage and suggest a possible application of SOE and its fractions as food supplements.
Characterization of the Phytochemical Composition and Bioactivities of Anacyclus maroccanus Ball. and Anacyclus radiatus Loisel Aerial Parts: Preliminary Evidence for the Possible Development of…
In the present study, the phytochemical composition and bioactivities of A. maroccanus (AM) and A. radiatus (AR), two ecotypes collected in the Demnate road and Essaouira regions, respectively, were…
Chemopreventive Potential of Caryophyllane Sesquiterpenes: An Overview of Preliminary Evidence
Emerging evidence has outlined a complex polypharmacological profile of caryophyllane sesquiterpenes characterized by blocking, suppressing, chemosensitizing, and cytoprotective properties, which suggests a possible usefulness of these natural substances in cancer chemoprevention for both preventive and adjuvant purposes.
Chemosensitizing Properties of β-Caryophyllene and β-Caryophyllene Oxide in Combination with Doxorubicin in Human Cancer Cells.
A potential role of CRY and CRYO as new chemosensitizing agents for doxorubicin chemotherapy and to re-sensitize cancer-resistant cells is highlighted.
Cassia angustifolia Extract Is Not Hepatotoxic in an in vitro and in vivo Study
A lack of hepatotoxicity of senna at doses higher than those generally used in humans is indicated, in summary, the present study indicates.