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Que PASA? The posterior-anterior shift in aging.
A consistent finding from functional neuroimaging studies of cognitive aging is an age-related reduction in occipital activity coupled with increased frontal activity. This posterior-anterior shiftExpand
Task-independent and task-specific age effects on brain activity during working memory, visual attention and episodic retrieval.
It is controversial whether the effects of aging on various cognitive functions have the same common cause or several different causes. To investigate this issue, we scanned younger and older adultsExpand
Triple dissociation in the medial temporal lobes: recollection, familiarity, and novelty.
Memory for past events may be based on retrieval accompanied by specific contextual details (recollection) or on the feeling that an item is old (familiarity) or new (novelty) in the absence ofExpand
Brain Activity during Episodic Retrieval of Autobiographical and Laboratory Events: An fMRI Study using a Novel Photo Paradigm
Functional neuroimaging studies of episodic memory retrieval generally measure brain activity while participants remember items encountered in the laboratory (controlled laboratory condition) orExpand
The spatiotemporal dynamics of autobiographical memory: neural correlates of recall, emotional intensity, and reliving.
We sought to map the time course of autobiographical memory retrieval, including brain regions that mediate phenomenological experiences of reliving and emotional intensity. Participants recalledExpand
Effects of healthy aging on hippocampal and rhinal memory functions: an event-related fMRI study.
Event-related functional magnetic resonance imaging was used to study the effects of healthy aging on hippocampal and rhinal memory functions. Memory for past events can be based on retrievalExpand
When less means more: deactivations during encoding that predict subsequent memory
In event-related functional MRI (fMRI) studies, greater activity for items that are subsequently remembered (R-items) than for items That are subsequently forgotten (F-items), or Dm effect (Difference in memory), has been attributed to successful encoding operations. Expand
Neural Correlates of Relational Memory: Successful Encoding and Retrieval of Semantic and Perceptual Associations
Using event-related functional magnetic resonance imaging, we identified brain regions involved in successful relational memory (RM) during encoding and retrieval for semantic and perceptualExpand
Similar network activated by young and old adults during the acquisition of a motor sequence
In this functional MRI (fMRI) study, we investigated ageing effects on motor skill learning. We applied an adapted version of the serial reaction time (SRT) task to extensive groups of young (N=26)Expand
Neuroanatomical correlates of episodic encoding and retrieval in young and elderly subjects.
Lesion studies have shown convincingly that the medial temporal lobes (MTL) and frontal lobes are critical to episodic memory. Ageing generally has been found to have a generally negative effect onExpand