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MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2
MicroRNAs function as negative regulators of posttranscriptional gene expression, having major roles in cellular differentiation. Several neuroblastoma cell lines can be induced to undergoExpand
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Reversible induction of translational isoforms of p53 in glucose deprivation
Tumor suppressor protein p53 is a master transcription regulator, indispensable for controlling several cellular pathways. Earlier work in our laboratory led to the identification of dual internalExpand
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p53 amyloid formation leading to its loss of function: implications in cancer pathogenesis
The transcriptional regulator p53 has an essential role in tumor suppression. Almost 50% of human cancers are associated with the loss of p53 functions, where p53 often accumulates in the nucleus asExpand
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Role of 5-lipoxygenase in resveratrol mediated suppression of 7,12-dimethylbenz(α)anthracene-induced mammary carcinogenesis in rats.
Substantial evidences suggest that lipoxygenase-catalyzed products have a strong influence on the development and progression of human cancers. The dietary phytochemical resveratrol has become aExpand
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The interplay between transcription and mRNA degradation in Saccharomyces cerevisiae
The cellular transcriptome is shaped by both the rates of mRNA synthesis in the nucleus and mRNA degradation in the cytoplasm under a specified condition. The last decade witnessed an excitingExpand
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Vanadium in Cancer Prevention
The pharmacological role of vanadium in health and disease remains one of the fascinating stories in biology. Recent studies have established vanadium as a novel regulator in assessing physiologicalExpand
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Biological activity of carotenoids: its implications in cancer risk and prevention.
Recently nontoxic natural compounds are getting immense importance for the prevention of diseases of different etiology. Natural product provitamin A "carotenoids", largely α-carotene, β-carotene,Expand
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Overexpression of 5‐lipoxygenase and its relation with cell proliferation and angiogenesis in 7,12‐dimethylbenz(α)anthracene‐induced rat mammary carcinogenesis
The present study was performed to investigate the critical role of 5‐lipoxygenase (5‐LOX) in 7,12‐dimethylbenz(α)anthracene (DMBA)‐induced rat mammary inflammation associated carcinogenesis. FemaleExpand
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Combined supplementation of vanadium and fish oil suppresses tumor growth, cell proliferation and induces apoptosis in DMBA‐induced rat mammary carcinogenesis
The anti‐cancer activity of vanadium and fish oil has been shown in a large number of studies. This study was undertaken to analyze the combined effect of vanadium and fish oil onExpand
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Cell Alignment on Graphene–Amyloid Composites
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