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Chemical studies on Cucurbita moschata Duch. I. The isolation and structural studies of cucurbitine, a new amino acid.
The antiatherogenic effects of components isolated from pollen typhae.
12 components isolated from Pollen Typhae have been identified on their chemical structures and biological effects and 4 of them showed different evident antiatherogenic effects, providing some information for the search of new drugs in the treatment and prevention of atherosclerosis. Expand
Inhibitors of DNA topoisomerase I isolated from the roots of Zanthoxylum nitidum
A methanol extract of Zanthoxylum nitidum found to inhibit topoisomerase I-mediated DNA relaxation and stabilize the covalent binary complex between the enzyme and DNA was subjected to… Expand
[Brain dopamine depleted by d-tetrahydropalmatine].
- S. Xu, G. Jin, L. P. Yu, G. X. Liu, W. Lu, S. D. Fang
- Chemistry, Medicine
- Zhongguo yao li xue bao = Acta pharmacologica…
- 1 May 1987
l-Tetrahydropalmatine(l-THP) is a DA receptor antagonist, which could antagonize both contralateral rotation induced by amphetamine (Amp) and ipsilateral rotation challenged by apomorphine (Apo) in… Expand
Further study of pollen typhae's effects on the production of tPA and PGI, by cultured endothelial cells.
The data indicated that the mechanisms of Pollen Typhae in its antiatherosclerotic effects were multiple which resulted from various biologic effects exerted by various components of this drug. Expand
Three diterpene dilactone glycosides from Podocarpus nagi.
Three water-soluble constituents, nagilactosides C-E, were isolated from Podocarpus nagi. Their structures were determined by chemical and spectroscopic methods, respectively. Nagilactoside C was… Expand
Studies on the active principles of Schisandra sphenanthera Rehd. et Wils. The structures of schisantherin A, B, C, D, E, and the related compounds.
In pharmacologica studies and preliminary clinical trials, schisantherin A, B, C, and D showed good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis, while deoxyschisandrin (VIII) and five new lignans were not effective. Expand
[The application of circular dichroism on the structure analysis of natural products--diterpenoid dilactones and tylophorines].
- J. Mi, S. D. Fang, Y. Chen, Y. M. Xu, R. Zhang
- Chemistry, Medicine
- Yao xue xue bao = Acta pharmaceutica Sinica
Using circular dichroism, sector projection and reverse octant rule projection of four diterpenoid dilactones and five tylophorines, the predicted effects of these compounds coincided with the result of previous determinations, so, their absolute configurations are assigned. Expand
Sesquiterpene lactones from dicoria canescens
Abstract Dicoria canescens from Baja California, Mexico afforded the known monoterpene glucoside, (−)- cis -chrysanthenol O -β- d -glucopyranoside, ivalbatin, a xanthanolide and two new sesquiterpene… Expand