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Rumen microbial community composition varies with diet and host, but a core microbiome is found across a wide geographical range
TLDR
There were few strong co-occurrence patterns between microbes, suggesting that major metabolic interactions are non-selective rather than specific, and could make it possible to mitigate methane emissions by developing strategies that target the few dominant methanogens. Expand
Erratum: Rumen microbial community composition varies with diet and host, but a core microbiome is found across a wide geographical range
TLDR
There were few strong co-occurrence patterns between microbes, suggesting that major metabolic interactions are non-selective rather than specific, and could make it possible to mitigate methane emissions by developing strategies that target the few dominant methanogens. Expand
Overexpression of Protective Antigen as a Novel Approach To Enhance Vaccine Efficacy of Brucella abortusStrain RB51
TLDR
Strain RB51 overexpressing SOD (RB51SOD) was tested in BALB/c mice for its ability to protect against challenge infection with virulent strain 2308 and developed significantly more resistance to challenge than those vaccinated with strain RB51 alone. Expand
Cloning of Brucella abortus gene and characterization of expressed 26-kilodalton periplasmic protein: potential use for diagnosis.
TLDR
Using molecular biology techniques, a gene that encodes a 26-kDa protein that is in the periplasm of B. abortus and in transformed Escherichia coli might be of value as an antigen for serological diagnosis of brucellosis in different mammals. Expand
Characterization of Specific Immune Responses of Mice Inoculated with Recombinant Vaccinia Virus Expressing an 18-Kilodalton Outer Membrane Protein of Brucella abortus
TLDR
It is suggested that the 18-kDa protein plays no role in protective immunity and is unlikely to affect either the strain's protective capabilities or its in vivo attenuation characteristics. Expand
Protection levels in vaccinated heifers with experimental vaccines Brucella abortus M1-luc and INTA 2.
TLDR
Results indicate that in bovines BP26 had no influence in protective capacity of S19, correlating with the results obtained in mice and contrarily to what was previously observed in mice, lack of expression of Omp19 rendered in less protection capacity ofS19 in the natural host. Expand
The TolC Homologue of Brucella suis Is Involved in Resistance toAntimicrobial Compounds and Virulence
TLDR
Results suggest that BepC-dependent efflux processes of toxic compounds contribute to B. suis survival inside the host. Expand
Identification and Characterization of a Brucella abortus ATP-Binding Cassette Transporter Homolog to Rhizobium meliloti ExsA and Its Role in Virulence and Protection in Mice
TLDR
Using the genomic survey sequence (GSS) approach, the gene encoding an ATP-binding cassette (ABC) transporter of B. abortus ExsA was identified and placed in ortholog group 6 of ABC transporters more likely to be involved in bacterial pathogenesis. Expand
A novel 27 kDa lipoprotein antigen from Mycobacterium bovis.
TLDR
The results presented here and elsewhere suggest that mycobacterial lipoproteins should be considered in the design of new recombinant vaccines and diagnostic methods. Expand
Brucella abortus INTA2, a novel strain 19 Δbp26::luc Δbmp18 double mutant lacking drug resistance markers
TLDR
Results indicate that B. abortus INTA2 might be a promising vaccine strain against brucellosis, and would allow differentiation of InTA2-vaccinated animals from animals infected with field strains by measuring anti-BP26 antibodies, either by an agglutination test or ELISA using BP26 as antigen. Expand
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