• Publications
  • Influence
Motor insurance rating: An acturarial approach
  • S. Coutts
  • Economics, Computer Science
  • 1 June 1984
This paper is largely based on a Ph.D. thesis (Coutts (1983)) and provides an actuarial approach to the technical aspects of motor insurance premium rating, where equal weights are given to both the practical and statistical elements of the problem. Expand
  • 35
  • 5
Thermodynamics and kinetics of G-C base pairing in the isolated extra arm of serine-specific transfer RNA from yeast.
  • S. Coutts
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • 25 February 1971
Abstract The extra arm of serine-specific tRNA has been isolated and its helix-coil transition investigated. The oligonucleotide, which according to its clover-leaf structure contains 4 G·C baseExpand
  • 47
  • 3
REV 5901: an orally effective peptidoleukotriene antagonist, detailed biochemical/pharmacological profile.
REV 5901 [alpha-pentyl-3-(2-quinolinylmethoxy)-benzene-methanol] has been shown to be a competitive antagonist of peptidoleukotrienes. In vitro it has a Ki value of 0.7 microM vs. [3H]leukotriene D4Expand
  • 36
  • 1
Substituted arylmethyl phenyl ethers. 1. A novel series of 5-lipoxygenase inhibitors and leukotriene antagonists.
A series of new substituted arylmethyl phenyl ethers has been prepared. These compounds were tested as inhibitors of 5-lipoxygenase (5-LO) in rat neutrophils, in vitro antagonists ofExpand
  • 49
  • 1
Conjugates of double-stranded oligonucleotides with poly(ethylene glycol) and keyhole limpet hemocyanin: a model for treating systemic lupus erythematosus.
Two types of oligonucleotides were synthesized with linker groups attached at the 5'-end. Both were repeating dimers of deoxyribocytidine and deoxyriboadenosine. A 20-mer was prepared with aExpand
  • 37
  • 1
Carbonothioate phospholipids as substrate for a spectrophotometric assay of phospholipase A2.
A continuous spectrophotometric assay for phospholipase A2 (PLA2) was developed using novel carbonothioate phospholipids. These phospholipid analogues contain a carbonothioate bond in the place ofExpand
  • 8
  • 1
Loss of IgE receptors and shedding of a protease during purification of mast cells.
  • 5
  • 1
Antiallergic activity of tiaramide (RHC 2592-A).
Tiaramide (RHC 2592-A) is an analgesic agent with antiallergic activity in vivo. We have investigated the antianaphylactic properties of tiaramide and its metabolites in three in vitro models ofExpand
  • 11
The coupling of conformational transitions in alanine specific transfer ribonucleic acid from yeast studied by a modified differential absorption technique.
A high precision differential absorption technique has been developed for the detailed experimental analysis of the complex melting behaviour of specific tRNAs. This technique allows the resolutionExpand
  • 59