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Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient
Background Neural stem cells are currently being investigated as potential therapies for neurodegenerative diseases, stroke, and trauma. However, concerns have been raised over the safety of this… Expand
Radical excision of intramedullary spinal cord tumors: surgical morbidity and long-term follow-up evaluation in 164 children and young adults.
- S. Constantini, D. Miller, J. Allen, L. Rorke, D. Freed, F. Epstein
- Journal of neurosurgery
- 1 October 2000
OBJECT The majority of intramedullary spinal cord tumors (IMSCT) in children and young adults are low-grade gliomas. Radical resection of similar tumors in the cerebral hemisphere or cerebellum is… Expand
Altered adenosine-to-inosine RNA editing in human cancer.
Adenosine-to-inosine (A-to-I) RNA editing was recently shown to be abundant in the human transcriptome, affecting thousands of genes. Employing a bioinformatic approach, we identified significant… Expand
Genetic and clinical determinants of constitutional mismatch repair deficiency syndrome: report from the constitutional mismatch repair deficiency consortium.
BACKGROUND Constitutional mismatch repair deficiency (CMMRD) is a devastating cancer predisposition syndrome for which data regarding clinical manifestations, molecular screening tools and management… Expand
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers
DNA replication−associated mutations are repaired by two components: polymerase proofreading and mismatch repair. The mutation consequences of disruption to both repair components in humans are not… Expand
Diffusion tensor imaging in hydrocephalus: initial experience.
- Y. Assaf, L. Ben-Sira, S. Constantini, L. Chang, L. Beni-Adani
- AJNR. American journal of neuroradiology
- 1 September 2006
PURPOSE AND BACKGROUND Diffusion tensor imaging (DTI) is an MR imaging-based technique that provides an in vivo tool for visualization of white matter tracts. In this preliminary study, we used this… Expand
The role of motor evoked potentials during surgery for intramedullary spinal cord tumors.
- N. Morota, V. Deletis, S. Constantini, M. Kofler, H. Cohen, F. Epstein
- 1 December 1997
OBJECTIVE This is a prospective study of the methodology and clinical applications of motor evoked potentials (MEPs) during surgery for intramedullary spinal cord tumors. METHODS Transcranial… Expand
Endoscopic third ventriculostomy in patients with cerebrospinal fluid infection and/or hemorrhage.
OBJECT In this study the authors evaluate the safety, efficacy, and indications for endoscopic third ventriculostomy (ETV) in patients with a history of subarachnoid hemorrhage or intraventricular… Expand
Endoscopic third ventriculostomy in the treatment of childhood hydrocephalus.
- A. Kulkarni, J. Drake, C. Mallucci, S. Sgouros, J. Roth, S. Constantini
- The Journal of pediatrics
- 1 August 2009
OBJECTIVE To develop a model to predict the probability of endoscopic third ventriculostomy (ETV) success in the treatment for hydrocephalus on the basis of a child's individual characteristics. … Expand
Predicting who will benefit from endoscopic third ventriculostomy compared with shunt insertion in childhood hydrocephalus using the ETV Success Score.
- A. Kulkarni, J. Drake, J. Kestle, C. Mallucci, S. Sgouros, S. Constantini
- Journal of neurosurgery. Pediatrics
- 1 October 2010
OBJECT The authors recently developed and internally validated the ETV Success Score (ETVSS)--a simplified means of predicting the 6-month success rate of endoscopic third ventriculostomy (ETV) for a… Expand