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Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
TLDR
The results for 1990 and 2010 supersede all previously published Global Burden of Disease results and highlight the importance of understanding local burden of disease and setting goals and targets for the post-2015 agenda taking such patterns into account. Expand
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
TLDR
The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model. Expand
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
TLDR
Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades. Expand
Incidence, causes, and outcomes of dilated cardiomyopathy in children.
TLDR
In children, DCM is a diverse disorder with outcomes that depend largely on cause, age, and heart failure status at presentation, and race, sex, and age affect the incidence of disease. Expand
Recommendations for quantification methods during the performance of a pediatric echocardiogram: a report from the Pediatric Measurements Writing Group of the American Society of Echocardiography
TLDR
This educational activity is designed for all cardiovascular physicians and cardiac sonographers with erest and knowledge base in the field of echocardiography; in addition, reschers, clinicians, intensivists, and other medical professionals with a cardiac ultrasound will find this activity beneficial. Expand
Cardiomyocyte proliferation contributes to heart growth in young humans
TLDR
Examining the cellular growth mechanisms of the left ventricle on a set of healthy hearts from humans aged 0–59 y shows that cardiomyocyte proliferation contributes to developmental heart growth in young humans, suggesting that children and adolescents may be able to regenerate myocardium, and that abnormal cardiomeocyte proliferation may be involved in myocardial diseases that affect this population. Expand
Late cardiac effects of doxorubicin therapy for acute lymphoblastic leukemia in childhood.
TLDR
Doxorubicin therapy in childhood impairs myocardial growth in a dose-related fashion and results in a progressive increase in left ventricular afterload sometimes accompanied by reduced contractility, hypothesized to result in inadequateleft ventricular mass and clinically important heart disease in later years. Expand
A single intravenous infusion of gamma globulin as compared with four infusions in the treatment of acute Kawasaki syndrome.
TLDR
In children with acute Kawasaki disease, a single large dose of intravenous gamma globulin is more effective than the conventional regimen of four smaller daily doses and is equally safe. Expand
Theoretical and empirical derivation of cardiovascular allometric relationships in children.
TLDR
Body surface area was found to be a more important determinant of the size of each of the cardiovascular structures than age, height, or weight alone and fit a complex model predicted by the nonlinear decrease of heart rate with growth. Expand
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