S. Cohen

Publications71
h-index25
Citations1,744
Highly Influential Citations25
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The distribution of acetylcholine sensitivity over uninnervated and innervated muscle fibers grown in cell culture.
Abstract This paper describes the physiological and pharmacological parameters of the response of mature muscle fibers that develop from myoblasts in vitro to iontophoretically applied acetylcholine… Expand
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Role of asialo-GM1 positive liver cells from athymic nude or polyinosinic-polycytidylic acid-treated mice in suppressing colon-derived experimental hepatic metastasis.
Liver-derived (LD) murine colon adenocarcinoma MCA-38 cells injected into the ileocolic vein (ICV) of C57BL/6 mice developed distinct hepatic foci within 14-21 days and survived for an average of… Expand
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Correlation between adriamycin-induced augmentation of interleukin 2 production and of cell-mediated cytotoxicity in mice.
Based on the observation that spleen cells from Adriamycin-treated mice could develop augmented levels of cytotoxic T-lymphocyte activity in response to heat-treated and/or X-irradiated alloantigens,… Expand
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Early nerve-muscle synapses in vitro release transmitter over postsynaptic membrane having low acetylcholine sensitivity.
  • S. Cohen
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1980
Functional nerve-muscle synapses form rapidly in cultures of embryonic chicken spinal cord and muscle cells. As early as 30 min after nerve processes first contact muscle fibers they are able to… Expand
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Clusters of intramembrane particles associated with binding sites for alpha-bungarotoxin in cultured chick myotubes
Developing chick myotubes in tissue culture were freeze-fractured to yield complementary replicas of large areas of membrane. Regions of muscle fibers with high concentrations of acetylcholine… Expand
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n-butyrate reduces the expression of beta-galactoside alpha 2,6-sialyltransferase in Hep G2 cells.
n-Butyrate, a short chain fatty acid that is produced by colonic bacterial fermentation, is detectable in portal blood and induces differentiation in various human neoplastic cell lines. Earlier… Expand
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Selective Effects of Adriamycin on Murine Host Defense Systems
The clinical value of cancer chemotherapy is limited by the fact that the , anticancer agents available to date are not sufficiently selective in their antitumor action. Because of this, it may not… Expand
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Multiple tumoricidal effector mechanisms induced by adriamycin.
The antitumor cytotoxic mechanisms of Adriamycin-elicited peritoneal exudate cells were investigated. Peritoneal exudate cells from mice collected 1 day after an i.p. injection of Adriamycin (10… Expand
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Anti-DNA activity in systemic lupus erythematosus. A diagnostic and therapeutic guide.
Several autoantibodies have been associated with systemic lupus erythematosis (SLE). Attention has been directed in particular to antibodies reactive with desoxyribonucleic acid (DNA) (Seligmann,… Expand
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Cellular basis for adriamycin-induced augmentation of cell-mediated cytotoxicity in culture.
The cellular basis for the augmented cell-mediated cytotoxic (CMC) response seen when spleen cells from Adriamycin (ADM)-treated mice were stimulated in culture was investigated. Under conditions… Expand
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