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Interaction of the Arabidopsis Receptor Protein Kinase Wak1 with a Glycine-rich Protein, AtGRP-3*
The data suggest that AtGRP-3 regulates Wak1 function through binding to the cell wall domain of Wak1 and that the interaction of Wak 1 with AtGRp-3 occurs in a pathogenesis-related process in planta.
Antioxidant and antiproliferative activities of mango (Mangifera indica L.) flesh and peel
The antioxidant and antiproliferative properties of flesh and peel of mango (Mangifera indica L.) were investigated. The cytoprotective effect of mango flesh and peel extracts on oxidative damage
Functional regulation of Slug / Snail2 is dependent on GSK‐3β‐mediated phosphorylation
This study suggests that GSK‐3β‐mediated phosphorylation of Slug/Snail2 controls its turnover and localization during EMT.
Quercetin Induces Mitochondrial Mediated Apoptosis and Protective Autophagy in Human Glioblastoma U373MG Cells
Pretreatment with chloroquine, an autophagy inhibitor, strongly augmented apoptosis in U373MG cells, indicating that quercetin induced protective autopagy in U 373MG cells.
Comparative antioxidant and antiproliferative activities of red and white pitayas and their correlation with flavonoid and polyphenol content.
There was a direct correlation between the phenolic content and antioxidant effect, but no correlation observed between antioxidant activity and antiproliferative activity, suggesting that the peel of white and red pitaya may be a valuable ingredient in foods and may also be useful in cosmetic, nutraceutical, and pharmaceutical applications.
β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation.
The findings suggest that CPO can interfere with multiple signaling cascades involved in tumorigenesis and used as a potential therapeutic candidate for both the prevention and treatment of cancer.
Metabolite profiling of red and white pitayas (Hylocereus polyrhizus and Hylocereus undatus) for comparing betalain biosynthesis and antioxidant activity.
TPC, TFC, TBC, and betalain-related metabolites were suggested to be the main contributors to antioxidant activity in pitayas, suggesting peels as well as pulp of pitaya could beneficially help in the food industry.
Cytotoxic Activity of β -Caryophyllene Oxide Isolated from Jeju Guava (Psidium cattleianum Sabine) Leaf
β-caryophyllene oxide was isolated from the leaf of the Jeju guava (Psidium cattleianum Sabine) for the first time in this study. The chemical structure was confirmed with the help of various
Noble tandem-repeat galectin of Manila clam Ruditapes philippinarum is induced upon infection with the protozoan parasite Perkinsus olseni.
Noble galectin (MCGal) was cloned from the marine invertebrate Ruditapes philippinarum and characterized, and Carbohydrate recognition by the recombinant MCGal (rMCGal), as determined by hapten inhibition of hemagglutination, revealed that rMCGal has features common to the galECTin family, i.e., significant affinity for galactose and N-acetylgalactosamine.
Mechanistic investigation on the toxicity of MgO nanoparticles toward cancer cells
Magnesium oxide nanoparticles (MgO NPs) are increasingly recognized for their applications in cancer therapy such as nano-cryosurgery and hyperthermia. The present study investigated the cytotoxic