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Prion protein expression and functional importance in developmental angiogenesis: role in oxidative stress and copper homeostasis.
AIM It has been convincingly shown that oxidative stress and toxicity by deregulated metals, such as copper (Cu), are tightly linked to the development of pre-eclampsia and intrauterine growthExpand
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Revisiting the role of hCG: new regulation of the angiogenic factor EG-VEGF and its receptors
Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) is an angiogenic factor reported to be specific for endocrine tissues, including the placenta. Its biological activity is mediatedExpand
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Second Messenger-Operated Calcium Entry Through TRPC6.
Canonical transient receptor potential 6 (TRPC6) proteins assemble into heteromultimeric structures forming non-selective cation channels. In addition, many TRPC6-interacting proteins have beenExpand
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Corrigendum: Pharmacological Characterization of the Native Store-Operated Calcium Channels of Cortical Neurons from Embryonic Mouse Brain
[This corrects the article on p. 486 in vol. 7, PMID: 28018223.].
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Lipid nanocapsules containing the non-ionic surfactant Solutol HS15 inhibit the transport of calcium through hyperforin-activated channels in neuronal cells
Hyperforin is described as a natural antidepressant inhibiting the reuptake of neurotransmitters and also activating cation channels. However the blood-brain barrier limits the access to the brain ofExpand
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Pharmacological Characterization of the Native Store-Operated Calcium Channels of Cortical Neurons from Embryonic Mouse Brain
In the murine brain, the first post-mitotic cortical neurons formed during embryogenesis express store-operated channels (SOCs) sensitive to Pyr3, initially proposed as a blocker of the transientExpand
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EG-VEGF, BV8, and their receptor expression in human bronchi and their modification in cystic fibrosis: Impact of CFTR mutation (delF508).
Enhanced lung angiogenesis has been reported in cystic fibrosis (CF). Recently, two highly homologous ligands, endocrine gland vascular endothelial growth factor (EG-VEGF) and mammalian Bv8, haveExpand
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The Na+/K+-ATPase and the amyloid-beta peptide aβ1-40 control the cellular distribution, abundance and activity of TRPC6 channels.
The Na(+)/K(+)-ATPase interacts with the non-selective cation channels TRPC6 but the functional consequences of this association are unknown. Experiments performed with HEK cells over-expressingExpand
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Involvement of the Prion Protein in the Protection of the Human Bronchial Epithelial Barrier Against Oxidative Stress.
Aim: Bronchial epithelium acts as a defensive barrier against inhaled pollutants and microorganisms. This barrier is often compromised in inflammatory airway diseases that are characterized byExpand
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EG-VEGF , BV 8 , and their receptor expression in human bronchi and their modification in cystic fibrosis : Impact of CFTR mutation ( delF 508 )
Sylvain Chauvet, Wael Traboulsi, Laura Thevenon, Amal Kouadri, Jean-Jacques Feige, Boubou Camara, Nadia Alfaidy, and Mohamed Benharouga Centre National de la Recherche Scientifique, LCBM-UMR 5249,Expand
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