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Regulation of Human Vascular Endothelial Growth Factor mRNA Stability in Hypoxia by Heterogeneous Nuclear Ribonucleoprotein L*
A 126-base region of human vascular endothelial growth factor (VEGF) 3′-untranslated region, which we identified as the hypoxia stability region, forms seven hypoxia-inducible RNA-protein complexes… Expand
Nonvascular role for VEGF: VEGFR-1, 2 activity is critical for neural retinal development.
- G. Robinson, M. Ju, +4 authors L. E. Smith
- Biology, Medicine
- FASEB journal : official publication of the…
- 1 May 2001
SPECIFIC AIMSVEGF is critical for angiogenesis and is commonly described as endothelial cell specific; however, there is accumulating evidence that VEGF receptors are found outside the vasculature ...
Role of AP-1 and HIF-1 Transcription Factors in TGF-β Activation of VEGF Expression
Abstract Aberrant expression of vascular endothelial growth factor (VEGF) has been demonstrated to be associated with most human solid tumors. Here we report that TGF-β potently induces VEGF… Expand
Hypoxia‐mediated regulation of gene expression in mammalian cells
- S. C. Shih, K. Claffey
- Biology, Medicine
- International journal of experimental pathology
- 1 December 1998
The molecular mechanism underlying oxygen sensing in mammalian cells has been extensively investigated in the areas of glucose transport, glycolysis, erythropoiesis, angiogenesis and catecholamine… Expand
Effect of Isoflavone Aglycone Content and Antioxidation Activity in Nattoby Various Cultures of Bacillus Subtilis During the Fermentation Period
This study investigated the isoflavone aglycones content and antioxidant activities (total phenol, 1,1-diphenyl- 2-picrylhydrazyl (DPPH) free radical-scavenging activity and… Expand
Role of protein kinase C isoforms in phorbol ester-induced vascular endothelial growth factor expression in human glioblastoma cells.
- S. C. Shih, A. Mullen, K. Abrams, D. Mukhopadhyay, K. Claffey
- The Journal of biological chemistry
Aberrant expression of the potent angiogenic cytokine, vascular endothelial growth factor (VEGF), has been demonstrated to be associated with most human solid tumors. Both transcriptional and… Expand