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  • H Inoue, Jackie Ferrer, +9 authors M. Alan Permutt
  • Biology, Medicine
  • Diabetes
  • 1997 (First Publication: 1 March 1997)
  • Signals derived from the metabolism of glucose in pancreatic β-cells lead to insulin secretion via the closure of ATP-sensitive K+ channels (KATP). The cloning of the gene encoding the (β-cell inwardContinue Reading
  • Hua Wang, Winston S. Chu, Chris Hemphill, S. C. Elbein
  • Medicine, Biology
  • The Journal of clinical endocrinology and…
  • 2002 (First Publication: 1 June 2002)
  • Insulin resistance is strongly associated with obesity, but even among obese subjects insulin sensitivity varies widely. Recently, a new adipocyte hormone, resistin, was identified, shown to reduceContinue Reading
  • Hua Wang, Zhengxian Zhang, Winston S. Chu, Terri C Hale, Judith J Cooper, S. C. Elbein
  • Biology, Medicine
  • The Journal of clinical endocrinology and…
  • 2005 (First Publication: 1 February 2005)
  • IL-6 levels and polymorphisms have been implicated in type 2 diabetes mellitus (T2DM) and insulin resistance. The IL-6 receptor (IL-6R) comprises two subunits, IL-6R and gp130, of which IL-6R confersContinue Reading