S. Butcher

Publications171
h-index46
Citations6,114
Highly Influential Citations370
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A mechanism for initiating RNA-dependent RNA polymerization
In most RNA viruses, genome replication and transcription are catalysed by a viral RNA-dependent RNA polymerase. Double-stranded RNA viruses perform these operations in a capsid (the polymerase… Expand
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Insights into assembly from structural analysis of bacteriophage PRD1
The structure of the membrane-containing bacteriophage PRD1 has been determined by X-ray crystallography at about 4 Å resolution. Here we describe the structure and location of proteins P3, P16, P30… Expand
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Molecular Mechanisms of Membrane Deformation by I-BAR Domain Proteins
BACKGROUND Generation of membrane curvature is critical for the formation of plasma membrane protrusions and invaginations and for shaping intracellular organelles. Among the central regulators of… Expand
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Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity
Another host factor for SARS-CoV-2 Virus-host interactions determine cellular entry and spreading in tissues. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the earlier SARS-CoV use… Expand
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Structure and host-cell interaction of SH1, a membrane-containing, halophilic euryarchaeal virus
The Archaea, and the viruses that infect them, are the least well understood of all of the three domains of life. They often grow in extreme conditions such as hypersaline lakes and sulfuric hot… Expand
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Insights into virus evolution and membrane biogenesis from the structure of the marine lipid-containing bacteriophage PM2.
Recent, primarily structural observations indicate that related viruses, harboring no sequence similarity, infect hosts of different domains of life. One such clade of viruses, defined by common… Expand
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Electron Cryotomography of Tula Hantavirus Suggests a Unique Assembly Paradigm for Enveloped Viruses
ABSTRACT Hantaviruses (family Bunyaviridae) are rodent-borne emerging viruses that cause a serious, worldwide threat to human health. Hantavirus diseases include hemorrhagic fever with renal syndrome… Expand
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Architecture of respiratory syncytial virus revealed by electron cryotomography
Human respiratory syncytial virus is a human pathogen that causes severe infection of the respiratory tract. Current information about the structure of the virus and its interaction with host cells… Expand
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Structure of the archaeal head-tailed virus HSTV-1 completes the HK97 fold story
It has been proposed that viruses can be divided into a small number of structure-based viral lineages. One of these lineages is exemplified by bacterial virus Hong Kong 97 (HK97), which represents… Expand
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Virion Architecture Unifies Globally Distributed Pleolipoviruses Infecting Halophilic Archaea
ABSTRACT Our understanding of the third domain of life, Archaea, has greatly increased since its establishment some 20 years ago. The increasing information on archaea has also brought their viruses… Expand
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