Photoisomerization in different classes of azobenzene.
- H. Bandara, S. Burdette
- ChemistryChemical Society Reviews
- 13 February 2012
This critical review details the studies completed to date on the 3 main classes of azobenzene derivatives and explains the mechanism behind the isomerization mechanism.
Fluorescent sensors for Zn(2+) based on a fluorescein platform: synthesis, properties and intracellular distribution.
- S. Burdette, G. Walkup, B. Spingler, R. Tsien, S. Lippard
- Chemistry, BiologyJournal of the American Chemical Society
- 24 July 2001
The X-ray crystal structure of a 2:1 Zn(2+):Zinpyr-1 complex has been solved, and is the first structurally characterized example of a complex of fluorescein substituted with metal binding ligands, making them well-suited for intracellular applications.
ZP4, an improved neuronal Zn2+ sensor of the Zinpyr family.
- S. Burdette, C. Frederickson, W. Bu, S. Lippard
- ChemistryJournal of the American Chemical Society
- 22 January 2003
A second-generation fluorescent sensor for Zn(2+) from the Zinpyr family, ZP4, has been synthesized and characterized and a 5-fold fluorescent enhancement is observed under simulated physiological conditions corresponding to the binding of the Zn (2+) cation to the sensor, which inhibits a photoinduced electron transfer (PET) quenching pathway.
A New Cell-Permeable Fluorescent Probe for Zn2+
- G. Walkup, S. Burdette, S. Lippard, R. Tsien
- Biology, Chemistry
- 27 May 2000
Although Zn2+ is abundant in eukaryotes and most is tightly bound, pools of chelatable Zn 2+ have been imaged in living cells with concentrations ranging from sub-nM in undifferentiated mammalian…
Proof for the concerted inversion mechanism in the trans-->cis isomerization of azobenzene using hydrogen bonding to induce isomer locking.
- H. Bandara, Tracey R Friss, S. Burdette
- ChemistryJournal of Organic Chemistry
- 16 July 2010
These molecules provide important supporting evidence for the spectroscopic and computational studies aimed at elucidating the isomerization mechanism in azobenzene.
Meeting of the minds: Metalloneurochemistry
- S. Burdette, S. Lippard
- Chemistry, BiologyProceedings of the National Academy of Sciences…
- 24 March 2003
Metalochaperones help to achieve metal ion homeostasis and thus prevent neurological diseases because of metal ion imbalance and much detailed chemical information about these systems has become available recently.
Bright fluorescent chemosensor platforms for imaging endogenous pools of neuronal zinc.
- Christopher J. Chang, Elizabeth M. Nolan, J. Jaworski, S. Burdette, Morgan Sheng, S. Lippard
- Biology, ChemistryChemistry and Biology
- 1 February 2004
The rhodafluor family. An initial study of potential ratiometric fluorescent sensors for Zn2+.
- S. Burdette, S. Lippard
- ChemistryInorganic Chemistry
- 20 November 2002
Although only small shifts in absorption wavelength were observed, the intensity doubling makes the probe of value for immediate application in situations where the previous tight binding (<1 nM) sensors are inadequate.
Method for identifying neuronal cells suffering zinc toxicity by use of a novel fluorescent sensor
- C. Frederickson, S. Burdette, S. Lippard
- BiologyJournal of Neuroscience Methods
- 15 October 2004
Photochemical tools for studying metal ion signaling and homeostasis.
- Hannah W. Mbatia, S. Burdette
- Chemistry, BiologyBiochemistry
- 5 September 2012
Photochemical tools such as small molecule and protein-based fluorescent sensors as well as photocaged complexes have provided insight into the homeostasis and signaling mechanisms of Ca, Zn, and Cu, but a comprehensive picture of metal ions in biology will require additional development of these techniques.
...
...