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Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons
Cell surface proteolysis is essential for communication between cells and results in the shedding of membrane‐protein ectodomains. However, physiological substrates of the contributing proteases areExpand
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Organic azides : syntheses and applications
Forewords: Rolf Huisgen, Valery Fokin, and Barry Sharpless. Preface. List of Contributors. Abbreviations. PART 1: SYNTHESIS AND SAFETY. 1 Lab-Scale Synthesis of Azido Compounds: Safety Measures andExpand
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Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function
Metzincin metalloproteases have major roles in intercellular communication by modulating the function of membrane proteins. One of the proteases is the a-disintegrin-and-metalloprotease 10 (ADAM10)Expand
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Chemistry and biology of mycotoxins and related fungal metabolites.
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Antibacterial activity of sulfamethoxazole transformation products (TPs): general relevance for sulfonamide TPs modified at the para position.
Sulfonamide antibiotics undergo transformation in the aquatic environment through biodegradation, photolysis, or hydrolysis. In this study, the residual antibacterial activity of 11 transformationExpand
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Secretome Analysis Identifies Novel Signal Peptide Peptidase-Like 3 (SPPL3) Substrates and Reveals a Role of SPPL3 in Multiple Golgi Glycosylation Pathways*
Signal peptide peptidase-like 3 (SPPL3) is a Golgi-resident intramembrane-cleaving protease that is highly conserved among multicellular eukaryotes pointing to pivotal physiological functions in theExpand
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Synthesis, structure, and characterization of dinuclear copper(I) halide complexes with P^N ligands featuring exciting photoluminescence properties.
A series of highly luminescent dinuclear copper(I) complexes has been synthesized in good yields using a modular ligand system of easily accessible diphenylphosphinopyridine-type P^N ligands.Expand
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Xanthones from fungi, lichens, and bacteria: the natural products and their synthesis.
Many fungi, lichens, and bacteria produce xanthones (derivatives of 9H-xanthen-9-one, “xanthone” from the Greek “xanthos”, for “yellow”) as secondary metabolites. Xanthones are typicallyExpand
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Platinum nanoparticles and their cellular uptake and DNA platination at non-cytotoxic concentrations
Three differently sized, highly dispersed platinum nanoparticle (Pt-NP) preparations were generated by supercritical fluid reactive deposition (SFRD) and deposited on a β-cyclodextrin matrix. TheExpand
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A novel series of isoreticular metal organic frameworks: realizing metastable structures by liquid phase epitaxy
A novel class of metal organic frameworks (MOFs) has been synthesized from Cu-acetate and dicarboxylic acids using liquid phase epitaxy. The SURMOF-2 isoreticular series exhibits P4 symmetry, for theExpand
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