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Nanosuspension for improving the bioavailability of a poorly soluble drug and screening of stabilizing agents to inhibit crystal growth.
The purpose of this study was to develop a nanosuspension of a poorly soluble drug by nanomilling process using wet media milling to achieve superior in vitro dissolution and high in vivo exposure inExpand
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Formulation optimization and topical delivery of quercetin from solid lipid based nanosystems.
The presence of large amounts of reactive oxygen species (ROS) leads to oxidative stress that can damage cell membranes, lead to DNA breakage and cause inactivation of free radical scavenger enzymes,Expand
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Optimization of formulation and process parameters for the production of nanosuspension by wet media milling technique: effect of Vitamin E TPGS and nanocrystal particle size on oral absorption.
The purpose of this study was to develop nanosuspension formulations of a poorly soluble drug using a wet media milling technique. The milling process was optimized by studying the effects ofExpand
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Preparation and characterization of lipid based nanosystems for topical delivery of quercetin.
The main objective of this study was to evaluate the potential of lipid nanosystems for topical delivery of the naturally occurring flavonoid quercetin. These lipid based nanosystems wereExpand
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Association Between Adherence to the Mediterranean Diet and Asthma in Peruvian Children
PurposeAdherence to a Mediterranean diet pattern may be associated with lower asthma prevalence in children. We sought to corroborate these findings in Peruvian children.MethodsThis case–controlExpand
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Exploring quality of life in critically ill tracheostomy patients: a pilot study.
BACKGROUND Tracheostomies are performed to improve health-related quality of life (QOL) in patients requiring prolonged mechanical ventilation. As the lengths of stay in intensive care units (ICU)Expand
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Prenatal particulate matter exposure and wheeze in Mexican children: Effect modification by prenatal psychosocial stress.
BACKGROUND Air pollution exposure in childhood is associated with greater incidence and exacerbation of asthma, particularly in children whose parents report high levels of psychological stress.Expand
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Prenatal fine particulate exposure and early childhood asthma: Effect of maternal stress and fetal sex
Background The impact of prenatal ambient air pollution on child asthma may be modified by maternal stress, child sex, and exposure dose and timing. Objective We prospectively examined associationsExpand
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Spray granulation: importance of process parameters on in vitro and in vivo behavior of dried nanosuspensions.
The use of fluid bed granulation for drying of pharmaceutical nanoparticulates on micron-sized granule substrates is a relatively new technique, with limited understanding in the current literatureExpand
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Anticoagulation, Bleeding, Mortality, and Pathology in Hospitalized Patients With COVID-19
Background Thromboembolic disease is common in coronavirus disease-2019 (COVID-19). There is limited evidence on the association of in-hospital anticoagulation (AC) with outcomes and postmortemExpand
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