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Enoxaparin vs unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy: primary results of the SYNERGY
TLDR
Enoxaparin was not superior to unfractionated heparin but was noninferior for the treatment of high-risk patients with non-ST-segment elevation ACS and the advantages of convenience should be balanced with the modest excess of major bleeding. Expand
Ninety-Minute Exclusion of Acute Myocardial Infarction By Use of Quantitative Point-of-Care Testing of Myoglobin and Troponin I
TLDR
Acute myocardial infarction can be excluded rapidly in the emergency department by use of point-of-care measurements of myoglobin and troponin I during the first 90 minutes after presentation. Expand
Determinants of mortality after myocardial infarction in patients with advanced renal dysfunction.
TLDR
The excess mortality in this population appears to be mediated through arrhythmias, adverse hemodynamic events, and the lower use of mortality-reducing therapy. Expand
Benefits of aspirin and beta-blockade after myocardial infarction in patients with chronic kidney disease.
TLDR
ASA+BB is an underused therapy in patients with acute myocardial infarction who have underlying kidney disease who are more likely to be male, free of earlier cardiac disease, and recipients of thrombolysis. Expand
Improving quality of care for acute myocardial infarction: The Guidelines Applied in Practice (GAP) Initiative.
TLDR
Implementation of guideline-based tools for AMI may facilitate quality improvement among a variety of institutions, patients, and caregivers and provides a foundation for future initiatives aimed at quality improvement. Expand
Analysis of long-term survival after revascularization in patients with chronic kidney disease presenting with acute coronary syndromes.
TLDR
Patients with severe CKD and ACS had improved long-term survival when treated with percutaneous coronary revascularization, associated with superior long- term survival. Expand
Prevention of peripheral venous catheter complications with an intravenous therapy team: a randomized controlled trial.
TLDR
An IV therapy team significantly reduced both local and bacteremic complications of peripheral IV catheters, and timely replacement of the catheter appeared to be the most important factor in reducing the occurrence of complications. Expand
TIMI Myocardial Perfusion Grade and ST Segment Resolution: Association With Infarct Size as Assessed by Single Photon Emission Computed Tomography Imaging
TLDR
There may be a pathophysiological link between early restoration of tissue-level perfusion and reduced subsequent infarct size that may partially explain why these early angiographic and electrocardiographic measures are associated with long-term survival. Expand
Preliminary experience with intravenous P2Y12 platelet receptor inhibition as an adjunct to reduced-dose alteplase during acute myocardial infarction: results of the Safety, Tolerability and Effect
TLDR
This first experience with the intravenous P2Y12 receptor inhibitor, cangrelor, suggests the potential of this compound as an adjunct to fibrinolysis during treatment of AMI. Expand
Relation of age and race with hospital death after acute myocardial infarction.
TLDR
Blacks younger than 65 years had higher hospital mortality rates compared with whites hospitalized for AMI, and decreasing age was associated with progressively higher risk of hospital death for blacks. Expand
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