• Publications
  • Influence
Functional MRI of language: new approaches to understanding the cortical organization of semantic processing.
  • S. Bookheimer
  • Psychology, Medicine
  • Annual review of neuroscience
  • 2002
Three lines of fMRI research into how the semantic system is organized in the adult brain are discussed, which broaden the understanding of how the brain stores, retrieves, and makes sense of semantic information and challenge some commonly held notions of functional modularity in the language system. Expand
Understanding emotions in others: mirror neuron dysfunction in children with autism spectrum disorders
High-functioning children with autism and matched controls underwent fMRI while imitating and observing emotional expressions, suggesting that a dysfunctional 'mirror neuron system' may underlie the social deficits observed in autism. Expand
The Autism Brain Imaging Data Exchange: Towards Large-Scale Evaluation of the Intrinsic Brain Architecture in Autism
W Whole-brain analyses reconciled seemingly disparate themes of both hypo- and hyperconnectivity in the ASD literature; both were detected, although hypoconnectivity dominated, particularly for corticocortical and interhemispheric functional connectivity. Expand
Patterns of brain activation in people at risk for Alzheimer's disease.
Patterns of brain activation during tasks requiring memory differ depending on the genetic risk of Alzheimer's disease and may predict a subsequent decline in memory. Expand
Modulating emotional responses: effects of a neocortical network on the limbic system
Functional MRI results provide evidence for a network in which higher regions attenuate emotional responses at the most fundamental levels in the brain and suggest a neural basis for modulating emotional experience through interpretation and labeling. Expand
Remembering episodes: a selective role for the hippocampus during retrieval
It is shown that activity in the hippocampus increased only when retrieval was accompanied by conscious recollection of the learning episode, indicating that the hippocampus selectively supports the retrieval of episodic memories. Expand
Recruitment of anterior dorsolateral prefrontal cortex in human reasoning: a parametric study of relational complexity.
Functional magnetic resonance imaging is used to identify brain regions that respond selectively in processing high levels of relational complexity and provides evidence that brain regions specific to integrating complex relations among stimuli are distinct from those involved in coping with general task difficulty and with working-memory demands. Expand
Early developmental emergence of human amygdala–prefrontal connectivity after maternal deprivation
It is demonstrated that, as in the rodent, children who experienced early maternal deprivation exhibit early emergence of mature amygdala–prefrontal connectivity, suggesting that accelerated amygdala–mPFC development is an ontogenetic adaptation in response to early adversity. Expand
Form and Content Dissociating Syntax and Semantics in Sentence Comprehension
The findings strongly indicate that a part of Broca's area is critically implicated in processing syntactic information, whereas the lower portion of the left inferior frontal gyrus is selectively involved in processing the semantic aspects of a sentence. Expand
The Neural Correlates of Motor Skill Automaticity
The results showed that supplementary motor area and putamen/globus pallidus regions showed training-related decreases for sequence conditions but not for random conditions, confirming the role of these regions in the representation of learned motor sequences. Expand