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Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine.
TLDR
This vaccine was efficacious in preventing rotavirus gastroenteritis, decreasing severe disease and health care contacts, and the risk of intussusception was similar in vaccine and placebo recipients. Expand
Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children
TLDR
This heptavalent pneumococcal conjugate appears to be highly effective in preventing invasive disease in young children and to have a significant impact on otitis media. Expand
Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children. Northern California Kaiser Permanente Vaccine Study Center Group.
TLDR
This heptavalent pneumococcal conjugate appears to be highly effective in preventing invasive disease in young children and to have a significant impact on otitis media. Expand
Effectiveness of heptavalent pneumococcal conjugate vaccine in children younger than five years of age for prevention of pneumonia
TLDR
The heptavalent CRM197 pneumococcal conjugate vaccine was given to infants at 2, 4, 6 and 12 to 15 months of age in a randomized, double blind trial and was effective in reducing the risk of pneumonia in young children. Expand
Impact of the pneumococcal conjugate vaccine on otitis media
TLDR
In children followed up to 3.5 years, PCV provided a moderate amount of protection against ear infections while reducing frequent otitis media and tube procedures by greater amounts. Expand
Influenza and the rates of hospitalization for respiratory disease among infants and young children.
TLDR
Infants and young children without chronic or serious medical conditions are at increased risk for hospitalization during influenza seasons, and routine influenza vaccination should be considered in these children. Expand
Postlicensure Surveillance for Pneumococcal Invasive Disease After Use of Heptavalent Pneumococcal Conjugate Vaccine in Northern California Kaiser Permanente
TLDR
The PNCV7 vaccine is highly effective in reducing the burden of pneumococcal disease in children <5 years of age, and there is evidence of a herd effect as well as a decrease in the antibiotic resistant in strains causing disease. Expand
Changing Epidemiology of Outpatient Bacteremia in 3- to 36-Month-Old Children After the Introduction of the Heptavalent-Conjugated Pneumococcal Vaccine
TLDR
New guidelines are needed to approach the previously healthy febrile toddler in the outpatient setting as the incidence of pneumococcal bacteremia has decreased, E. coli, Salmonella spp. Expand
Cost-effectiveness of a routine varicella vaccination program for US children.
TLDR
A routine varicella vaccination program for healthy children would result in net savings from the societal perspective, which includes work-loss costs as well as medical costs, and would also be relatively cost-effective from the health care payer's perspective. Expand
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