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Tobacco-specific and betel nut-specific N-nitroso compounds: occurrence in saliva and urine of betel quid chewers and formation in vitro by nitrosation of betel quid.
In order to evaluate exposure of betel quid chewers to N-nitroso compounds, saliva and urine samples were collected from chewers of betel quid with or without tobacco, from tobacco chewers, fromExpand
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Correlation of mutagenicity and tumorigenicity of betel quid and its ingredients.
The mutagenic activity of betel quid and its ingredients was determined using Salmonella typhimurium tester strains TA 100, TA 1535, TA 98, and TA 1538, both in the presence and absence of S9Expand
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Protective effect of food additives on aflatoxin-induced mutagenicity and hepatocarcinogenicity.
Food additives such as turmeric (Curcuma longa), and active ingredient curcumin (diferuloyl methane), asafoetida (flavouring agent), butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) andExpand
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Effect of turmeric oil and turmeric oleoresin on cytogenetic damage in patients suffering from oral submucous fibrosis.
In vitro studies on the effect of alcoholic extracts of turmeric (TE), turmeric oil (TO) and turmeric oleoresin (TOR), on the incidence of micronuclei (Mn) in lymphocytes from normal healthy subjectsExpand
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Antimutagenic effects of betel leaf extract against the mutagenicity of two tobacco-specific N-nitrosamines.
Epidemiological studies have implicated chewing tobacco alone to be more hazardous than chewing tobacco with betel quid. Experimental studies have shown that betel leaf is antimutagenic againstExpand
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Hydroxychavicol: a new phenolic antimutagen from betel leaf.
The phenolic compounds eugenol and hydroxychavicol were separated from betel leaf extract using C18 phase bonded Hiflosil silica gel. The structures of the two compounds were confirmed by nuclearExpand
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Mutagenicity of gingerol and shogaol and antimutagenicity of zingerone in Salmonella/microsome assay.
Ginger extract and its constituents gingerol, shogaol and zingerone were tested in Salmonella typhimurium strains TA 100, TA 98, TA 1535 and TA 1538 in the presence and in absence of S9 mix. It wasExpand
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Mutagenicity of betel quid and its ingredients using mammalian test systems.
The mutagenic potential of betel quid and its ingredients (known colloquially as PAN) were tested in two short term mutagenicity assays, the micronucleus test and a mammalian gene mutation test.Expand
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Anticarcinogenic effect of betel leaf extract against tobacco carcinogens.
Epidemiological studies have implicated that betel quid offers some protection to tobacco induced carcinogenesis. Earlier studies in our laboratory have shown betel leaf extract (BLE) to beExpand
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Mutagenicity of chili extract and capsaicin in short-term tests.
Vanillin, capsaicin and chili extracts were tested for mutagenicity in Salmonella typhimurium histidine-deficient tester strains TA 98, TA 100, TA 1535, TA 1537, and TA 1538. Vanillin wasExpand
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