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- Publications
- Influence
BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons
- N. Alikhan, Nicola K. Petty, Nouri L. Ben Zakour, S. Beatson
- Biology, Medicine
- BMC Genomics
- 8 August 2011
BackgroundVisualisation of genome comparisons is invaluable for helping to determine genotypic differences between closely related prokaryotes. New visualisation and abstraction methods are required… Expand
Easyfig: a genome comparison visualizer
- M. J. Sullivan, Nicola K. Petty, S. Beatson
- Computer Science, Medicine
- Bioinform.
- 28 January 2011
TLDR
Genome sequence of the Brown Norway rat yields insights into mammalian evolution
- R. Gibbs, G. Weinstock, +225 authors F. Collins
- Biology, Medicine
- Nature
- 1 April 2004
The laboratory rat (Rattus norvegicus) is an indispensable tool in experimental medicine and drug development, having made inestimable contributions to human health. We report here the genome… Expand
An extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their dissemination
- T. Tobe, S. Beatson, +9 authors M. Pallen
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 3 October 2006
Several pathogenic strains of Escherichia coli exploit type III secretion to inject “effector proteins” into human cells, which then subvert eukaryotic cell biology to the bacterium's advantage. We… Expand
Global dissemination of a multidrug resistant Escherichia coli clone
- Nicola K. Petty, Nouri L. Ben Zakour, +17 authors S. Beatson
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 31 March 2014
Significance Escherichia coli sequence type 131 (ST131) is a globally disseminated multidrug-resistant clone associated with human urinary tract and bloodstream infections. Here, we have used genome… Expand
Accelerated Evolution of the Prdm9 Speciation Gene across Diverse Metazoan Taxa
- P. Oliver, L. Goodstadt, +7 authors C. Ponting
- Biology, Medicine
- PLoS genetics
- 1 December 2009
The onset of prezygotic and postzygotic barriers to gene flow between populations is a hallmark of speciation. One of the earliest postzygotic isolating barriers to arise between incipient species is… Expand
Bioinformatics analysis of the locus for enterocyte effacement provides novel insights into type-III secretion
- M. Pallen, S. Beatson, C. M. Bailey
- Biology, Medicine
- BMC Microbiology
- 9 March 2005
BackgroundLike many other pathogens, enterohaemorrhagic and enteropathogenic strains of Escherichia coli employ a type-III secretion system to translocate bacterial effector proteins into host cells,… Expand
Bioinformatics, genomics and evolution of non-flagellar type-III secretion systems: a Darwinian perspective.
- M. Pallen, S. Beatson, C. Bailey
- Biology, Medicine
- FEMS microbiology reviews
- 1 April 2005
We review the biology of non-flagellar type-III secretion systems from a Darwinian perspective, highlighting the themes of evolution, conservation, variation and decay. The presence of these systems… Expand
A commensal gone bad: complete genome sequence of the prototypical enterotoxigenic Escherichia coli strain H10407.
- Lisa C. Crossman, R. Chaudhuri, +17 authors I. Henderson
- Biology, Medicine
- Journal of bacteriology
- 1 November 2010
In most cases, Escherichia coli exists as a harmless commensal organism, but it may on occasion cause intestinal and/or extraintestinal disease. Enterotoxigenic E. coli (ETEC) is the predominant… Expand
FpvB, an alternative type I ferripyoverdine receptor of Pseudomonas aeruginosa.
- Bart Ghysels, Bui Thi Min Dieu, +4 authors P. Cornelis
- Biology, Medicine
- Microbiology
- 1 June 2004
Under conditions of iron limitation, Pseudomonas aeruginosa secretes a high-affinity siderophore pyoverdine to scavenge Fe(III) in the extracellular environment and shuttle it into the cell. Uptake… Expand