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c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate.
myc−/− rat fibroblasts (KO cells) differ from myc+/+ (WT) cells and KO cells with enforced Myc re-expression (KO-Myc cells) with respect to mitochondrial structure and function, utilization ofExpand
Molecular cloning and sequencing of 25 different rhesus macaque chemokine cDNAs reveals evolutionary conservation among C, CC, CXC, AND CX3C families of chemokines.
Chemokines are small chemoattractant cytokines involved in normal and pathological immune processes. Although extensive nucleotide sequence data are available for human and murine chemokine cDNAExpand
A trans-spliced telomerase RNA dictates telomere synthesis in Trypanosoma brucei
Telomerase is a ribonucleoprotein enzyme typically required for sustained cell proliferation. Although both telomerase activity and the telomerase catalytic protein component, TbTERT, have beenExpand
Specific binding of monomeric bacteriophage T3 and T7 RNA polymerases to their respective cognate promoters requires the initiating ribonucleoside triphosphate (GTP).
Bacteriophage T3 and T7 RNA polymerases are monomeric proteins of Mr of about 100,000. Each polymerase has stringent specificity for its own promoters that is present only on the homologous phage DNAExpand
Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be rescued by treatment with mitochondria-targeted electron scavengers
Abstract Very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency is the most common defect of mitochondrial long-chain fatty acid β-oxidation. Patients present with heterogeneous clinicalExpand
Increased expression of interferon-inducible genes in macaque lung tissues during simian immunodeficiency virus infection.
Pulmonary infections and dysfunction are frequent outcomes during the development of immunodeficiency associated with human immunodeficiency virus type 1 (HIV-1) infection, and obtaining a betterExpand
c-Myc Programs Fatty Acid Metabolism and Dictates Acetyl-CoA Abundance and Fate*
Background: Cells lacking c-Myc demonstrate metabolic abnormalities marked by reduced glycolysis, oxidative phosphorylation, and proliferation. Results: These cells preferentially utilize fatty acidsExpand
Nucleotide sequence of a major class-III phage-T3 RNA-polymerase promoter located at 98.0% of phage-T3 genetic map.
The entire nucleotide sequence of a 409-bp HincII fragment, located within the MboI-E fragment on bacteriophage T3 DNA and containing a major class-III T3 RNA polymerase promoter positioned at 98% onExpand
Location, function, and nucleotide sequence of a promoter for bacteriophage T3 RNA polymerase.
The major promoters for bacteriophage T3 RNA polymerase on the T3 genome have been mapped by DNA.RNA filter hybridization. One promoter is located in a 300-base-pair Hpa I restriction fragment nearExpand
Regulation of alpha- and beta-tubulin mRNAs in rat brain during synaptogenesis.
Developmental alterations in alpha- and beta-tubulin mRNA in polysomes from brains of -3 days (fetal) to 30-day-old rats were quantitated by using well-characterized chicken alpha- and beta-tubulinExpand