• Publications
  • Influence
Matrix solid-phase dispersion.
  • S. Barker
  • Chemistry, Medicine
  • Journal of chromatography. A
  • 14 July 2000
TLDR
The present article provides a review of MSPD applications in these and related fields and discusses the factors known to affect M SPD methods. Expand
Autonomic, Neuroendocrine, and Immunological Effects of Ayahuasca: A Comparative Study With d-Amphetamine
TLDR
In conclusion, ayahuasca displayed moderate sympathomimetic effects, significant neuroendocrine stimulation, and a time-dependent modulatory effect on cell-mediated immunity. Expand
Applications of matrix solid-phase dispersion in food analysis.
  • S. Barker
  • Chemistry, Medicine
  • Journal of chromatography. A
  • 2 June 2000
Matrix solid-phase dispersion (MSPD), a patented process for the simultaneous disruption and extraction of solid and semi-solid samples, was first reported in 1989. Since that time, MSPD has foundExpand
Heparanase Degrades Syndecan-1 and Perlecan Heparan Sulfate
TLDR
It is demonstrated that cell-surface syndecan-1 and ECM perlecan are degradative targets of HPSE-1, and syndeca-1 regulates HPSe-1 biological activity, which suggest that expression of syndecans-1 on the melanoma cell surface and its degradation by HPS e-1 are important determinants in the control of tumor cell invasion and metastasis. Expand
A critical review of reports of endogenous psychedelic N, N-dimethyltryptamines in humans: 1955-2010.
TLDR
A critical review of 69 published studies reporting the detection or detection and quantitation of these compounds in human body fluids addresses the methods applied and the criteria used in the determination of the presence of DMT, MDMT, and HDMT. Expand
Metabolism and disposition of N,N-dimethyltryptamine and harmala alkaloids after oral administration of ayahuasca.
TLDR
The present results show the existence in humans of alternative metabolic routes for DMT other than biotransformation by MAO and that O-demethylation plus conjugation is an important but probably not the only metabolic route for the harmala alkaloids in humans. Expand
Acute Biphasic Effects of Ayahuasca
TLDR
Ayahuasca was found to induce a biphasic effect in the brain and effects were significantly associated with circulating levels of ayahuasca’s chemical compounds, mostly N,N-dimethyltryptamine (DMT), harmine, harmaline and tetrahydroharmine and some of their metabolites. Expand
Bioavailability and pharmacokinetics of oral and injectable formulations of methadone after intravenous, oral, and intragastric administration in horses.
TLDR
Absorption of methadone in the small intestine in horses appeared to be limited owing to the low bioavailability after intragastric administration, which could lead to a more appropriate choice of administration route that would enhance analgesia and minimize adverse effects in horses. Expand
Isolation of drug residues from tissues by solid phase dispersion.
TLDR
The applicability of this approach for multidrug residue extraction from a single sample is demonstrated for compounds representing the organophosphate, benzimidazole anthelmintic and beta-lactam antibiotic drug classes. Expand
Metabolism of the hallucinogen N,N-dimethyltryptamine in rat brain homogenates.
TLDR
The reported extension of half-life and potentiation of DMT behavioral effects by iproniazid may be due to inhibition of NMT and DMT-NO formation rather than inhibition of monoamine oxidase. Expand
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