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Multicenter, randomized, controlled trial of virtual-reality simulator training in acquisition of competency in colonoscopy.
TLDR
Fellows who underwent GI Mentor training performed significantly better during the early phase of real colonoscopy training, and a mixed-effects model demonstrated a higher objective competence overall in the simulator group. Expand
Evaluation of Factors That Have Reduced Mortality From Acute Pancreatitis Over the Past 20 Years
TLDR
There has been considerable reduction in the mortality associated with acute pancreatitis over the past 20 years, and recognition of severity signs, early implementation of organ-specific therapy, and newer endoscopic, surgical, and angiographic therapy for infection cyst and bleeding appear to have been the major factors in reducing mortality. Expand
Preliminary evaluation of safety and activity of recombinant human interleukin 11 in patients with active Crohn's disease.
TLDR
The thrombocytopoietic effect of rhIL-11 seems to be both dose and schedule dependent and may be minimized with retained clinical benefit in Crohn's disease at 16 microgram. Expand
Cytokines (IL-6, IL-8, TNF): Early and Reliable Predictors of Severe Acute Pancreatitis
TLDR
IL-6, IL-8, and TNF can be used independently in differentiating mild acute pancreatitis from early severe acute Pancreatitis. Expand
Clinical and hormonal aspects of pancreatic diabetes.
TLDR
The danger of drug-induced hypoglycemia, coupled with the infrequency of vasculopathy, retinopathy and nephropathy in pancreatic diabetes has induced us to keep these patients hyperglycemic and glycosuric rather than in a sugar-free state, as long as symptoms are contained. Expand
Combined ligation and sclerotherapy versus ligation alone for secondary prophylaxis of esophageal variceal bleeding: a meta-analysis
TLDR
The combination of ligation and sclerotherapy offers no advantage over ligation alone in prevention of rebleeding and in reduction of mortality, and is also associated with a higher complication rate of esophageal stricture. Expand
Fibreoptic endoscopy and the use of the Sengstaken tube in acute gastrointestinal haemorrhage in patients with portal hypertension and varices.
TLDR
The in-hospital survival rate was 52% in patients bleeding from varices and 64% in those bleeding from other causes, with an overall survival rate of 56%, indicating the poor prognosis in cirrhotic patients with gastrointestinal bleeding, irrespective of the cause. Expand
Causes of acute and recurrent pancreatitis. Clinical considerations and clues to diagnosis.
TLDR
The physician can whittle away at the idiopathic group by increasingly recognizing causes such as biliary sludge or microlithiasis, sphincter of Oddi dysfunction, hereditary pancreatitis, cystic fibrosis, or autoimmune causes. Expand
True incidence and clinical significance of pneumoperitoneum after PEG placement: a prospective study.
TLDR
The data suggest that pneumoperitoneum after PEG placement is common and, in the absence of clinical symptoms, is of no clinical significance and does not warrant any further intervention. Expand
Nutritional deficiencies in chronic pancreatitis.
TLDR
It appears from recent studies in Switzerland and other developed countries that mortality during a 12-year period may be in the region of 50 per cent worldwide, which may not be correctable even by hyperalimentation. Expand
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