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Orodispersible tablets: An overview
Oral drug delivery remains the preferred route for administration of various drugs. Recent developments in the technology have prompted scientists to develop orally disintegrating tablets (ODTs) withExpand
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Solid self-nanoemulsifying drug delivery system (S-SNEDDS) of darunavir for improved dissolution and oral bioavailability: In vitro and in vivo evaluation.
The current study was aimed to investigate the potential of solid self-nanoemulsifying drug delivery system (S-SNEDDS) composed of Capmul MCM C8 (oil), Tween 80 (surfactant) and Transcutol PExpand
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Oral self emulsifying powder of lercanidipine hydrochloride: Formulation and evaluation
The current investigation was aimed to improve the solubility of poorly soluble lercanidipine hydrochloride as self emulsifying powder (SEP). Liquid SEDDS of LCH was formulated with Capmul MCM L8 asExpand
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Bioavailability enhancement of zaleplon via proliposomes: Role of surface charge.
The present systematic study focused to investigate the combined advantage of proliposomes and surface charge for improved oral delivery of zaleplon. The zaleplon loaded proliposomes were preparedExpand
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Solubility enhancement and physicochemical characterization of carvedilol solid dispersion with Gelucire 50/13
The objective of the study was enhancement of dissolution of poorly soluble carvedilol by solid dispersions (SDs) with Gelucire 50/13 using solvent evaporation method. The solubility of carvedilolExpand
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Design and evaluation of polymeric coated minitablets as multiple unit gastroretentive floating drug delivery systems for furosemide.
A gastro retentive floating drug delivery system with multiple-unit minitablets based on gas formation technique was developed for furosemide. The system consists of core units (solid dispersion ofExpand
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A Gelucire 44/14 and labrasol based solid self emulsifying drug delivery system: formulation and evaluation
A solid self emulsifying formulation (S-SEF) has been developed with an intention to improve the dissolution characteristics of poorly water soluble lercanidipine hydrochloride (LH). SuitableExpand
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In situ absorption and relative bioavailability studies of zaleplon loaded self-nanoemulsifying powders
Self-nanoemulsifying drug delivery systems (SNEDDSs) offer potential as suitable carriers for improved oral delivery of poorly soluble and low bioavailable drugs. To derive self-nanoemulsifyingExpand
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Preparation of a crystalline salt of indomethacin and tromethamine by hot melt extrusion technology
Graphical abstract Figure. No caption available. ABSTRACT Although salt formation is the most ubiquitous and effective method of increasing the solubility and dissolution rates of acidic and basicExpand
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Enhanced bioavailability of exemestane via proliposomes based transdermal delivery.
Exemestane, a novel steroidal aromatase inactivator used in the treatment of advanced breast cancer has limited bioavailability (42%) due to poor solubility, extensive first-pass metabolism, and alsoExpand
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