• Publications
  • Influence
Mutations in Dynein Link Motor Neuron Degeneration to Defects in Retrograde Transport
Degenerative disorders of motor neurons include a range of progressive fatal diseases such as amyotrophic lateral sclerosis (ALS), spinal-bulbar muscular atrophy (SBMA), and spinal muscular atrophyExpand
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A Marked Improvement: transforming assessment in higher education.
A Marked Improvement has been developed by a group of experts, working with the HEA to provide a strong rationale for transforming assessment in higher education. It includes an assessment reviewExpand
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The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome.
The X chromosome-linked scurfy (sf) mutant of the mouse is recognized by the scaliness of the skin from which the name is derived and results in death of affected males at about 3-4 weeks of age.Expand
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Use of a novel real-time quantitative reverse transcription-polymerase chain reaction method to study the effects of cytokines on cytochrome P450 mRNA expression in mouse liver.
In this study, we developed a real-time quantitative reverse transcription-polymerase chain reaction (RT-PCR) method to study cytochrome P450 (CYP) mRNA regulation by cytokines in mouse liver. TheExpand
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Interindividual variation in the metabolism of ethynylestradiol.
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Lipopolysaccharide-mediated modulation of cytochromes P450 in Stat1 null mice.
Signal transducer and activator of transcription (Stat), a family of transcriptional factors, has been demonstrated to play a critical role in gene regulation in response to inflammatory cytokines,Expand
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The German Octopus: The British Metal Corporation and the Next War, 1914-1939
  • S. Ball
  • Economics, Engineering
  • 20 August 2004
After World War I, the nonferrous metals trade played a critical role in Britain's preparations for a future European war. Yet it has attracted little attention. The British Metal Corporation (BMC)Expand
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Pharmacogenetics and drug metabolism
OD-PEP (a Fixed dose combination of Pantoprazole and Domperidone) contains Pantoprazole which is chemically sodium 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2pyridinyl)methyl]sulfinyl]-1H-benzimidazoleExpand
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Hypoglycaemia associated with anorexia nervosa.
A 41 year old woman with severe emaciation due to longstanding anorexia nervosa presented with recurrent hypoglycaemia. During an episode of hypoglycaemia, serum insulin and C peptide wereExpand
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Sequence characterization of ENU-induced mutants of glucose phosphate isomerase in mouse
Four of five mutations producing GPI1 null lethal phenotypes in the homozygous state, which were previously identified from the offspring of male mice, spermatogonially treated with N-ethylExpand
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