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Esculentins A & B, Two New Diterpenes from Casearia esculenta.
The structures of esculentins A and B, isolated from the twigs of Casearia esculenta (Samydaceae), have been elucidated. They are found to be… Expand
Synthesis of (±)-Praeruptorin A and Related Khellactone Derivatives
Improves Synthesis of (±)-Praeruptorin A and Other Khellactone Esters by Solvent-free DCC Reactions
Esters of 4'-acetylkhellactone such as (+)-praeruptorin A (2) were synthesised in considerably improved yields through use of a low tempeature solvent-free DCC esterification reaction
Isolation of the Antiinflammatory Principle of Heracleum candicans.
Activity of the ilicicolins against plant pathogenic fungi
Ilicicolins D, E, F, dechloroilicicolin D, ascofuranone and arthrichitin were isolated from the fermentation broth of Nectria sp (HIL Y 90 3333). The ilicicolins showed good fungicidal activity in… Expand
Compounds 18beta, 19beta-diacetyloxy-18alfa, 19alfa-epoxy-3,13 (16), 14-clerodatrien-2-one (Esculentin a) and 18beta, 19beta-diacetyloxy-18alfa, 19alfa-epoxy-3,12,14-…
LA PRESENTE INVENCION SE REFIERE A LOS COMPUESTOS 18-BETA, 19-BETA - DIACETILOXI - 18-ALFA, 19-ALFA - EPOXI - 3,13 (16), 14 CLERODATRIEN - 2- ONA (ESCULENTIN A) Y 18-BETA, 19-BE DIACETILOXI - 18-ALFA… Expand
HL 752: a potent and long-acting antispasmodic agent.
- S. Bal-Tembe, D. Bhedi, +5 authors A. V. Kulkarni
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 1 July 1997
Of the compounds synthesised, HL 752 showed the most potent and long-lasting antispasmodic activity and was selected as the candidate for clinical development. Expand
Synthesis of (.+-.)-Praeruptorin A (I) and Related Khellactone Derivatives.