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Insensitivity to future consequences following damage to human prefrontal cortex
Following damage to the ventromedial prefrontal cortex, humans develop a defect in real-life decision-making, which contrasts with otherwise normal intellectual functions. Currently, there is noExpand
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Dissociation Of Working Memory from Decision Making within the Human Prefrontal Cortex
We tested the hypothesis that cognitive functions related to working memory (assessed with delay tasks) are distinct from those related to decision making (assessed with a gambling task), and thatExpand
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Impairment of social and moral behavior related to early damage in human prefrontal cortex
The long-term consequences of early prefrontal cortex lesions occurring before 16 months were investigated in two adults. As is the case when such damage occurs in adulthood, the two early-onsetExpand
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Awareness of disease states following cerebral infarction, dementia, and head trauma: Standardized assessment
Abstract Awareness of cognitive and motor impairments was evaluated in 100 patients with cerebral infarction, dementia, or head trauma, using a standardized interview which elicited subjects'Expand
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Acquired Personality Disturbances Associated With Bilateral Damage to the Ventromedial Prefrontal Region
Personality changes in 7 participants with bilateral ventromedial prefrontal lesions (PF-BVM), 14 participants with prefrontal lesions but not bilateral ventromedial involvement (PF-NBVM), and 36Expand
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Troubled letters but not numbers. Domain specific cognitive impairments following focal damage in frontal cortex.
A well educated right-handed woman developed severe and stable alexia and agraphia following a circumscribed surgical lesion in the left premotor cortex. The lesion was located in Brodmann's field 6,Expand
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Impairments of emotion and real-world complex behavior following childhood- or adult-onset damage to ventromedial prefrontal cortex.
The behavioral syndrome resulting from damage to the ventromedial prefrontal (VM) region presents major challenges for clinical assessment and management, stemming from the absence of reliableExpand
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Pathological laughter and crying: a link to the cerebellum.
Patients with pathological laughter and crying (PLC) are subject to relatively uncontrollable episodes of laughter, crying or both. The episodes occur either without an apparent triggering stimulusExpand
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Visual dysfunction in Parkinson disease without dementia
Objective: To determine the profiles of visual dysfunction and their relationship to motor and cognitive dysfunction and to disability in mild to moderate Parkinson disease (PD) without dementia.Expand
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Wisconsin Card Sorting Test performance as a measure of frontal lobe damage.
We examined the sensitivity and specificity of the Wisconsin Card Sorting Test (WCST) as a measure of frontal lobe damage in 91 subjects with stable focal brain lesions. Anatomical information aboutExpand
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