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Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999.
TLDR
This study presents a meta-analysis of the Methacholine Challenge Pretest Questionnaire results to assess the response of the participants and recommend further studies to investigate its application in clinical practice.
An official American Thoracic Society clinical practice guideline: exercise-induced bronchoconstriction.
TLDR
Strong recommendations were made for a daily inhaled corticosteroid, a daily leukotriene receptor antagonist, or a mast cell stabilizing agent before exercise for patients with EIB.
Provocation by eucapnic voluntary hyperpnoea to identify exercise induced bronchoconstriction
TLDR
The International Olympic Committee Medical Commission (IOC-MC) requires notification for use of a β2 agonist at the Winter Olympic Games in Salt Lake City and must be accompanied by objective evidence that justifies the need to use one.
Exercise in elite summer athletes: Challenges for diagnosis.
TLDR
The findings suggest that the pathogenesis of EIB in elite athletes might be different from that of asthma, and as such, neither symptoms nor the methacholine challenge test should be used exclusively for identifying EIB.
Pathogenesis, prevalence, diagnosis, and management of exercise-induced bronchoconstriction: a practice parameter.
TLDR
This systematic review and meta-analyses show clear trends in prognosis for asthma patients using a simple, straightforward, and scalable approach that combines e-mail, telephone, and laboratory testing.
Methods for “Indirect” challenge tests including exercise, eucapnic voluntary hyperpnea, and hypertonic aerosols
TLDR
Indirect challenge tests identify those with potential for exercise-induced bronchoconstriction, an important problem for some occupations, such as the defence forces, fire fighters and the police force and for some athletic activities.
A new method for bronchial-provocation testing in asthmatic subjects using a dry powder of mannitol.
TLDR
The airway sensitivity to inhaled mannitol, the repeatability of the response, and the recovery after challenge in 43 asthmatic subjects 18 to 39 yr of age who had a 20% decrease in FEV1 in response to inhaling a 4.5% NaCl was studied.
Exercise-induced bronchoconstriction: Pathogenesis
TLDR
Accumulating evidence suggests that airway smooth muscle (ASM) becomes more sensitive as a result of repeated exposure to bulk plasma in response to airway injury from dehydration.
The mechanism of exercise-induced asthma is ...
TLDR
The osmotic and thermal theories come together by considering that inspiration of cold air not only cools the airways but also increases the numbers of airway generations becoming dehydrated in the humidifying process.
Inhaled mannitol improves lung function in cystic fibrosis.
TLDR
Inhaled mannitol treatment over a period of 2 weeks significantly improved lung function in patients with CF and was safe and well tolerated.
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