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Sequence and organization of the human mitochondrial genome
The complete sequence of the 16,569-base pair human mitochondrial genome is presented. The genes for the 12S and 16S rRNAs, 22 tRNAs, cytochrome c oxidase subunits I, II and III, ATPase subunit 6,… Expand
Irbesartan in patients with heart failure and preserved ejection fraction.
- B. Massie, P. Carson, +8 authors A. Ptaszynska
- The New England journal of medicine
- 4 December 2008
BACKGROUND Approximately 50% of patients with heart failure have a left ventricular ejection fraction of at least 45%, but no therapies have been shown to improve the outcome of these patients.… Expand
Linkage and comparative mapping of the locus controlling susceptibility towards E. coli F4ab/ac diarrhoea in pigs
In 1995, Edfors-Lilja and coworkers mapped the locus for the E. coli K88ab (F4ab) and K88ac (F4ac) intestinal receptor to pig chromosome 13 (SSC13). Using the same family material we have refined the… Expand
Clinical effects of endothelin receptor antagonism with bosentan in patients with severe chronic heart failure: results of a pilot study.
BACKGROUND Endothelin receptor antagonism produces favorable short-term hemodynamic effects in heart failure, but the clinical effects of longer term therapy have not been evaluated. METHODS AND… Expand
Associations of gender and etiology with outcomes in heart failure with systolic dysfunction: a pooled analysis of 5 randomized control trials.
- Camille G. Frazier, K. Alexander, +6 authors P. Douglas
- Journal of the American College of Cardiology
- 3 April 2007
OBJECTIVES This study sought to explore the gender-related differences in etiology and outcomes in chronic heart failure (HF) patients from 5 randomized trials. BACKGROUND Each year, 550,000 new… Expand
A large duplication associated with dominant white color in pigs originated by homologous recombination between LINE elements flanking KIT
The Dominant White (I/KIT) locus is one of the major coat color loci in the pig. Previous studies showed that the Dominant White (I) and Patch (IP) alleles are both associated with a duplication… Expand
Item response models for joint analysis of quality of life and survival.
A complication when assessing quality of life data longitudinally is that in many trials a substantial percentage of patients die before completing all of the assessments. Furthermore, a patient's… Expand
Chemical modification of a titanium (IV) oxide electrode to give stable dye sensitisation without a supersensitiser
SEMICONDUCTING electrodes stable in aqueous solution during the photoelectrochemical oxidation of water have generally been large-bandgap oxides, and their photosensitisation to visible light is of… Expand
A large-fragment porcine genomic library resource in a BAC vector
- S. Anderson, N. L. Lopez-Corrales, B. Gorick, A. Archibald
- Biology, Medicine
- Mammalian Genome
- 1 September 2000
Genome scanning experiments in pigs are defining quantitative trait loci (QTL) which contribute to the genetic variation in traits of economic or biological importance (Andersson et al. 1994; Walling… Expand
Fructose supports energy metabolism of some, but not all, axons in adult mouse optic nerve.
- Lynne Allen, S. Anderson, +4 authors A. Brown
- Chemistry, Medicine
- Journal of neurophysiology
- 1 March 2006
We used transmission electron microscopy (TEM) and electrophysiological techniques to characterize the morphology and stimulus-evoked compound action potential (CAP), respectively, of the adult mouse… Expand