• Publications
  • Influence
Dermatophagoides farinae Allergens Diversity Identification by Proteomics*
  • S. An, L. Chen, +6 authors R. Lai
  • Medicine, Biology
  • Molecular & Cellular Proteomics
  • 12 March 2013
The most important indoor allergens for humans are house dust mites (HDM). Fourteen Dermatophagoides farinae allergens (Der f 1–3, 6, 7, 10, 11, 13–18, and 22) are reported although more than 30Expand
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Raf‐interactome in tuning the complexity and diversity of Raf function
Raf kinases have been intensely studied subsequent to their discovery 30 years ago. The Ras‐Raf‐mitogen‐activated protein kinase/extracellular signal‐regulated kinase kinase‐extracellularExpand
  • 12
  • 3
Rap-Interacting Proteins are Key Players in the Rap Symphony Orchestra
Rap, a member of the Ras-like small G-protein family, is a key node among G-protein coupled receptors (GPCR), receptor tyrosine kinases (RTKs), ion channels and many other downstream pathways. RapExpand
  • 11
  • 2
Methods used to study the oligomeric structure of G-protein-coupled receptors
G-protein-coupled receptors (GPCRs), which constitute the largest family of cell surface receptors, were originally thought to function as monomers, but are now recognized as being able to act in aExpand
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  • Open Access
Purification and Characterization of Two New Allergens from the Venom of Vespa magnifica
Due to poor diagnostic facilities and a lack of medical alertness, allergy to Vespa wasps may be underestimated. Few allergens have been identified from Vespa wasps. Possible native allergen proteinsExpand
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  • 1
  • Open Access
Diagnostic accuracy of urine dipstick for proteinuria in older outpatients
Background The urine dipstick is widely used as an initial screening tool for the evaluation of proteinuria; however, its diagnostic accuracy has not yet been sufficiently evaluated. Therefore, weExpand
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  • 1
A-Raf: A new star of the family of raf kinases
Abstract The Ras-Raf-MEK-MAPK (mitogen-activated protein kinase)-signaling pathway plays a key role in the regulation of many cellular functions, including cell proliferation, differentiation andExpand
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  • 1
Biased signalling: the instinctive skill of the cell in the selection of appropriate signalling pathways.
GPCRs (G-protein-coupled receptors) are members of a family of proteins which are generally regarded as the largest group of therapeutic drug targets. Ligands of GPCRs do not usually activate allExpand
  • 16
  • 1
Emerging role of the Jun N‐terminal kinase interactome in human health
  • X. Guo, S. An, +4 authors T. Xu
  • Medicine, Biology
  • Cell biology international
  • 1 July 2018
The c‐Jun N‐terminal kinases (JNKs) are located downstream of Ras‐mitogen activated protein kinase signaling cascades. More than 20 years of study has shown that JNKs control cell fate and manyExpand
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G protein-coupled receptors as promising cancer targets.
G protein-coupled receptors (GPCRs) regulate an array of fundamental biological processes, such as growth, metabolism and homeostasis. Specifically, GPCRs are involved in cancer initiation andExpand
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