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Anti‐inflammatory, analgesic and anti‐oedematous effects of Lafoensia pacari extract and ellagic acid
- A. P. Rogerio, C. Fontanari, L. Faccioli
- Biology, MedicineThe Journal of pharmacy and pharmacology
- 1 September 2006
Results demonstrate potential therapeutic effects of L. pacari extract and ellagic acid, providing new prospects for the development of drugs to treat pain, oedema and inflammation.
Antimicrobial activity of terpenoids from Copaifera langsdorffii Desf. against cariogenic bacteria
Copalic acid was the most active compound displaying MIC values very promising against the main microorganisms responsible for dental caries and was pointed out as an important metabolite in the search for new effective anticariogenic agents.
Constituents of glandular trichomes of Tithonia diversifolia: relationships to herbivory and antifeedant activity.
Kaurenoic acid from Sphagneticola trilobata Inhibits Inflammatory Pain: effect on cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling…
It is demonstrated that 1 exhibits an analgesic effect in a consistent manner and that its mechanisms involve the inhibition of cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway.
Antimicrobial Evaluation of Diterpenes from Copaifera langsdorffii Oleoresin Against Periodontal Anaerobic Bacteria
Copalic acid has shown to be an important metabolite for the control of periodontal diseases, and the use of standardized extracts based on copaiba oleoresin with high CA contents can be a important strategy in the development of novel oral care products.
Copaifera reticulata oleoresin: Chemical characterization and antibacterial properties against oral pathogens.
Analysis of the mechanisms underlying the vasorelaxant action of kaurenoic acid in the isolated rat aorta.
Occurrence, chemical composition, biological activities and analytical methods on Copaifera genus-A review.
Hypotensive action of naturally occurring diterpenes: a therapeutic promise for the treatment of hypertension.
Diterpenes: a therapeutic promise for cardiovascular diseases.
- C. R. Tirapelli, S. Ambrósio, F. B. da Costa, A. M. de Oliveira
- ChemistryRecent patents on cardiovascular drug discovery
Diterpenes likely fulfil the definition of a pharmacological preconditioning class of compounds and give hope for the therapeutic use in cardiovascular diseases.