S. Alexandersen

Publications169
h-index49
Citations7,279
Highly Influential Citations471
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The pathogenesis and diagnosis of foot-and-mouth disease.
The pathogenesis of foot-and-mouth disease (FMD) is reviewed, taking account of knowledge gained from field and experimental studies and embracing investigations at the level of the virus, the cell,… Expand
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Investigation into the Role of Potentially Contaminated Feed as a Source of the First‐Detected Outbreaks of Porcine Epidemic Diarrhea in Canada
Summary In January 2014, approximately 9 months following the initial detection of porcine epidemic diarrhea (PED) in the USA, the first case of PED was confirmed in a swine herd in south‐western… Expand
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Aspects of the persistence of foot-and-mouth disease virus in animals--the carrier problem.
Foot-and-mouth disease virus (FMDV) is a member of the Aphthovirus genus in the Picornaviridae family. Seven distinct serotypes, each including a wide range of variants, have been defined. FMD,… Expand
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Detection of all seven serotypes of foot-and-mouth disease virus by real-time, fluorogenic reverse transcription polymerase chain reaction assay.
A fluorogenic RT-PCR (5'-nuclease probe-based) assay using a primer/probe set designed from the internal ribosomal entry site region of the virus genome was developed for the specific detection of… Expand
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Studies of quantitative parameters of virus excretion and transmission in pigs and cattle experimentally infected with foot-and-mouth disease virus.
Foot-and-mouth disease virus (FMDV) can be spread by a variety of mechanisms and the rate of spread, the incubation period and the severity of disease depend on a multitude of parameters, including… Expand
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Novel reverse transcription loop-mediated isothermal amplification for rapid detection of foot-and-mouth disease virus
Summary.Speed is paramount in the diagnosis of foot-and-mouth disease (FMD) and simplicity is required if a test is to be deployed in the field. The development of a one-step, reverse transcription… Expand
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Further studies to quantify the dose of natural aerosols of foot-and-mouth disease virus for pigs.
Foot-and-mouth disease virus (FMDV) can be spread by a variety of mechanisms, including wind. Simulation models, developed to predict the risk of airborne spread, have played an important part in… Expand
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Foot-and-mouth disease: host range and pathogenesis.
In this chapter the host range of foot-and-mouth disease (FMD) under natural and experimental conditions is reviewed. The routes and sites of infection, incubation periods and clinical and… Expand
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Replication and Clearance of Respiratory Syncytial Virus
Human respiratory syncytial virus is an important cause of severe respiratory disease in young children, the elderly, and in immunocompromised adults. Similarly, bovine respiratory syncytial… Expand
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Reassortant Highly Pathogenic Influenza A H5N2 Virus Containing Gene Segments Related to Eurasian H5N8 in British Columbia, Canada, 2014
In late November 2014 higher than normal death losses in a meat turkey and chicken broiler breeder farm in the Fraser Valley of British Columbia initiated a diagnostic investigation that led to the… Expand
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