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Structures of 1,4,13,16-tetraoxa-7,10-dithia[16](1,1')ruthenocenophane and its 1:2 HgCl2 complex.
The reaction of 1,1′-bis(6-chloro-1,4-dioxahexyl)ruthenocene with disodium 1,2-ethanedithiolate gave 1,4,13,16-tetraoxa-7,9-dithia[16](1,1′)ruthenocenophane (5) in 63% yield. The reaction of 5 withExpand
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The effect of macrocyclic polyethers on the alkylation of sodium 2-naphtholate.
The alkylation of sodium 2-naphtholate, in the presence of benzo-18-crown-6 or 4,7,13,16,21,24-hexaoxabicyclo[8.8.8]hexacosane is found to give high ratios of O/O+C alkylation when conducted in THF,Expand
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Synthesis and Properties of Gramicidin S Analogs Consisting of Eight Amino Acid Residues
Three cyclic octapeptides (des-Val1,1′-gramicidin S, des-Leu3,3′-gramicidin S and des-Val1, Leu3′-gramicidin S), showed no antibiotic activity. Although their CD spectra resembled each other, theyExpand
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Properties of synthetic analogs of gramicidin S containing L-serine or L-glutamic acid residue in place of L-ornithine residue.
In order to investigate the biological role of the delta-amino groups of the Orn residue in gramicidin S, the four analogs, [Ser2]-, [Ser2.2']-, [Glu2]- and [Glu2.2']-gramicidin S were synthesized byExpand
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Role of ring size on the secondary structure and antibiotic activity of gramicidin S.
In order to investigate the contribution of ring size to the secondary structure and antibiotic activity of gramicidin S, many analogs consisting of 6, 7, 8, 9, 11, 12, 13, and 14 amino acid residuesExpand
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Biomimetic synthesis of gramicidin S. Direct formation of the antibiotic from pentapeptide active esters having no protecting group on the side chain of the Orn residue
The direct formation of gramicidin S (GS) by the dimerization-cyclization of pentapeptide active esters having no protecting group on the side chain of the Orn residue was examined. Among the fiveExpand
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CD Spectra and Cyclization of Linear Pentapeptides as Gramicidin S Precursors with a Benzyloxycarbonyl Group on the Side Chain of Orn Residue
Five pentapeptides related to gramicidin S, H–Val–Orn(Z)–Leu–D-Phe–Pro–OH, H–Orn(Z)–Leu–D-Phe–Pro–Val–OH, H–Leu–D-Phe–Pro–Val–Orn(Z)–OH, H–D-Phe–Pro–Val–Orn(Z)–Leu–OH, andExpand
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The architecture of dinuclear Ni and Cu complexes: twisted and parallel forms controlled by the self-assembly of Schiff base ligands
Novel dinuclear complexes were synthesized through the self-assembly of macrocyclic Schiff base ligands and either nickel(II) or copper(II) ions. X-Ray structural analysis revealed that the complexesExpand
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