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- Publications
- Influence
Can ultrasonography or uroflowmetry predict which children with voiding dysfunction will have recurrent urinary tract infections?
PURPOSE
It has been suggested that in children with voiding dysfunction improper bladder emptying contributes to recurrent urinary tract infections (UTIs) and progressive renal scarring. Incomplete… Expand
Diversity of NKR expression in aging T cells and in T cells of the aged: The new frontier into the exploration of protective immunity in the elderly
- S. Abedin, Joshua J. Michel, B. Lemster, A. Vallejo
- Biology, Medicine
- Experimental Gerontology
- 1 July 2005
Aging in the immune system is characterized by the contraction of the lymphocyte repertoire, exemplified by long-lived oligoclonal T cells that pervade the peripheral circulation. T-cell receptor… Expand
Predictive value of bronchiolitis obliterans syndrome stage 0p in chronic graft-versus-host disease of the lung.
- S. Abedin, G. Yanik, +6 authors D. Couriel
- Medicine
- Biology of blood and marrow transplantation…
- 1 June 2015
Bronchiolitis obliterans syndrome (BOS) is a significant post-transplant complication with low survival. BOS stage 0p (BOS 0p) is a parameter detected on pulmonary function tests (PFTs) after lung… Expand
BET inhibitors in the treatment of hematologic malignancies: current insights and future prospects
- S. Abedin, Craig S. Boddy, H. Munshi
- Biology, Medicine
- OncoTargets and therapy
- 28 September 2016
The bromodomain and extra-terminal (BET) family of proteins are important epigenetic regulators involved in promoting gene expression of critical oncogenes. BET inhibitors have been demonstrated to… Expand
Efficacy, Toxicity, and Infectious Complications in Ruxolitinib-Treated Patients with Corticosteroid-Refractory Graft-versus-Host Disease after Hematopoietic Cell Transplantation.
- S. Abedin, E. McKenna, +9 authors M. Hamadani
- Medicine
- Biology of blood and marrow transplantation…
- 1 August 2019
Corticosteroid-refractory graft-versus-host disease (SR-GVHD) remains a significant source of morbidity after allogeneic hematopoietic cell transplantation. No standard therapy exists in this… Expand
Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo.
- E. Kościuczuk, Diana Saleiro, +7 authors Leonidas C Platanias
- Chemistry, Medicine
- Blood
- 21 July 2016
Mitogen-activated protein kinase interacting protein kinases (Mnks) play important roles in the development and progression of acute myeloid leukemia (AML) by regulating eukaryotic translation… Expand
Outcomes of Reduced-Intensity Conditioning Allogeneic Hematopoietic Cell Transplantation Performed in the Inpatient versus Outpatient Setting.
- Guru Subramanian Guru Murthy, P. Hari, +15 authors M. Hamadani
- Medicine
- Biology of blood and marrow transplantation…
- 1 April 2019
Allogeneic hematopoietic cell transplantation (allo-HCT) with reduced-intensity conditioning (RIC) is commonly performed as an inpatient procedure. The feasibility and outcomes of RIC allo-HCT in the… Expand
Leukemoid reaction in chronic myelomonocytic leukemia patients undergoing surgery: perioperative management recommendations.
- A. Patel, Erin M Pettijohn, S. Abedin, Evan Raps, M. Deininger
- Medicine
- Blood advances
- 9 April 2019
Key Points CMML patients comprise an elderly and frail patient population with comorbidities that often require surgical intervention. Postsurgical leukemoid reaction, a life-threatening complication… Expand
Ruxolitinib: a potential treatment for corticosteroid refractory acute graft-versus-host disease
- S. Abedin, M. Hamadani
- Medicine
- Expert opinion on investigational drugs
- 15 April 2020
ABSTRACT Introduction Allogeneic transplantation represents a potentially curative procedure for various lethal conditions; however, it is associated with serious immune mediated complications. The… Expand
EF-G-dependent GTPase on the ribosome. conformational change and fusidic acid inhibition.
- Hyuk-Soo Seo, S. Abedin, Detlev Kamp, D. Wilson, K. Nierhaus, B. Cooperman
- Biology, Medicine
- Biochemistry
- 1 February 2006
Protein synthesis studies increasingly focus on delineating the nature of conformational changes occurring as the ribosome exerts its catalytic functions. Here, we use FRET to examine such changes… Expand