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[Prebiotic properties of mannose and its effect on specific resistance].
Mannose has prebiotic effect; the ability of mannose to induce expression of pro- and anti-inflammatory cytokines gives evidence of immunostimulating properties of the monosaccharide. Expand
[Immunobiological properties of recombinant L peptide from the Pseudomonas aeruginosa outer membrane].
The gene encoding plasma membrane protein L (OprL) was cloned and expressed in E. coli. It was shown that the recombinant protein had immunogenic properties and protected laboratory animals fromExpand
[Characteristics of antigenic complexes of Staphylococcus aureus vaccine strains obtained in different cultivation conditions].
The usefulness of the developed technology for manufacturing staphylococcal complex of antigens with reactor cultivation of vaccine strains in full value medium with subsequent purification of antigenic complex from the biomass by microfiltration was demonstrated. Expand
[Effect of strain-producer and cultivation medium on cross antigenic activity of Streptococcus pneumoniae water soluble antigens].
The study resulted in the selection of a technologically simple method of production of pneumococcus antigens with high protein content and showed that only 1 of the studied preparations produced from a virulent strain with poorly expressed S. pneumoniae capsule during cultivation in semi-synthetic medium has the highest cross antigenic activity. Expand
[Study of immunogenic properties of recombinant outer membrane proteins F and L from Pseudomonas aeruginosa].
In rabbits immunized with chromatographically purified recombinant proteins mounted specific antibody response, rabbit sera inhibited growth of P. aeruginosa culture and in experiments in vivo protected mice from infection caused by this microorganism. Expand
[Obtaining of outer membrane protein I of Pseudomonas aeruginosa and assessment of its antigenic properties].
Gene of outer membrane protein I (OprI) of Pseudomonas aeruginosa was cloned in Escherichia coli cells. Synthesized protein OprI contained additional sequence of 6 histidines on the N-terminus, whichExpand
[Evaluation of properties of Pseudomonas aeruginosa recombinant outer membrane protein F (OprF)].
In vivo studies on mice showed that rabbit hyperimmune sera and recombinant OprF are both able to protect animals from intraperitoneal challenge with P. aeruginosa. Expand
[Preparation of Pseudomonas aeruginosa recombinant outer-membrane protein F and the study of its antigenic properties].
In Escherichia coli M15, the gene of P. aeruginosa recombinant outer-membrane protein F (OprF) was cloned and chromatographically purified on Ni-agarose and containing an additional sequence of 6 histidines on the N-end, and in the mice injected with this protein specific IgG antibodies were synthesized. Expand
[Analysis of biological properties of strains-producers of a number of Pseudomonas aeruginosa recombinant proteins].
The results obtained allow to consider the possibility of use of E. coli BL21-aTox3 strains-producers for production and isolation of candidate proteins for inclusion into vaccine against pseudomonas infection. Expand