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Blood analysis by Raman spectroscopy.
Concentrations of multiple analytes were simultaneously measured in whole blood with clinical accuracy, without sample processing, using near-infrared Raman spectroscopy. Spectra were acquired withExpand
An In-Depth Analysis of Raman and Near-Infrared Chemical Images of Common Pharmaceutical Tablets
  • S. Šašiċ
  • Chemistry, Medicine
  • Applied spectroscopy
  • 1 March 2007
This study reports on the application of Raman and near-infrared (NIR) imaging techniques for determining the spatial distribution of all (five) components in a common type of pharmaceutical tabletExpand
Studies on the structure of water using two-dimensional near-infrared correlation spectroscopy and principal component analysis.
The structure of water molecules in the pure liquid state has been subjected to extensive research for several decades. Questions still remain unanswered, however, and no single model has been foundExpand
Short-wave near-infrared spectroscopy of biological fluids. 1. Quantitative analysis of fat, protein, and lactose in raw milk by partial least-squares regression and band assignment.
The present study has aimed at providing new insight into short-wave near-infrared (NIR) spectroscopy of biological fluids. To do that, we analyzed NIR spectra in the 800-1,100-nm region of 100 rawExpand
Raman spectroscopy for noninvasive glucose measurements.
We report the first successful study of the use of Raman spectroscopy for quantitative, noninvasive ("transcutaneous") measurement of blood analytes, using glucose as an example. As an initialExpand
Defining a Strategy for Chemical Imaging of Industrial Pharmaceutical Samples on Raman Line-Mapping and Global Illumination Instruments
The performance of line-mapping and global illumination Raman systems for two pharmaceutical tablets and a powder blend are assessed in this study. The chemical images were obtained from the placebo,Expand
Chemical images: Technical approaches and issues
  • D. Clark, S. Šašiċ
  • Computer Science, Medicine
  • Cytometry. Part A : the journal of the…
  • 1 August 2006
Chemical mapping techniques using Raman microscopy are introduced, and using an example of a pharmaceutical tablet, the practical aspects of data collection and processing to produce chemical image of the sample are detailed. Expand
Detailed analysis of the online near-infrared spectra of pharmaceutical blend in a rotary tablet press feed frame.
The present study is an in-depth analysis of the online near-infrared (NIR) spectra acquired with a spectrometer mounted on the rotary tablet press feed frame. A 3.5% active pharmaceutical ingredientExpand
Raman, infrared, and near-infrared chemical imaging
Preface. Contributors. 1 Spectroscopic Theory for Chemical Imaging (M. J. Pelletier and C. C. Pelletier). Part I Hardware. 2 Raman Imaging Instrumentation (Matthew P. Nelson and Patrick J. Treado). 3Expand
A New Possibility of the Generalized Two-Dimensional Correlation Spectroscopy. 1. Sample-Sample Correlation Spectroscopy
In this paper an extension of the generalized two-dimensional (2D) correlation spectroscopy, sample−sample correlation spectroscopy, is proposed to obtain the information about the species'Expand