S Yeandle

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The voltage across the cell membrane of human T-lymphocyte cell lines was recorded by the whole cell patch clamp technique. We studied how this voltage fluctuated in time and found that these fluctuations have fractal characteristics. We used the Hurst rescaled range analysis and the power spectrum of the increments of the voltage (sampled at 0.01-sec(More)
Biochemical studies of K+ efflux from rat pinealocytes revealed for the first time that norepinephrine (NE) increases 86Rb+ and 42K+ efflux. The effects of NE depend upon concurrent activation of both alpha 1- and beta-adrenoceptors. This effect is mediated by cAMP and Ca2+, which appear to act in conjunction to control K+ efflux; studies with charybdotoxin(More)
Discrete waves of depolarizing membrane potential in arthropod photoreceptors, called quantum bumps, appear to result from single-photon absorptions of the visual pigment. Statistical analysis of bump records suggest a model for bump occurrence in dark-adapted receptors at low levels of illumination. This model assumes that a photon that isomerizes a visual(More)
Synaptic potentials were recorded extracellularly in in vitro frog cutaneous pectoris nerve muscle preparation in air at 1 ATA and in a hyperbaric gas environment of 1 ATA air plus 30 ATA helium. Sufficient curare was always used in the bathing solution to prevent propagated muscle action potentials upon maximal stimulation of the nerve. Shape of the(More)
A circuit for an electronic switch is described that suppresses large unwanted signals that might overload physiological amplifiers during recording of weak neural signals. The circuit, made from inexpensive and easily available integrated circuits, can be operated from any timer that produces at least a +5 volt output pulse. It operates by connecting a low(More)
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