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An increased risk of breast cancer in women with a family history of breast cancer has been demonstrated by many studies using a variety of study designs. However, the extent of this risk varies according to the nature of the family history (type of relative affected, age at which relative developed breast cancer and number of relatives affected) and may(More)
The results of the Swedish two-county trial of mammographic screening for breast cancer are presented, updated to December 31, 1990, which is an average of 10.8 years follow-up per person. The main result of the trial in terms of breast cancer mortality remained the same: compared with the control group, the group invited to screening had a relative breast(More)
BACKGROUND Several studies have found a smaller effect of breast cancer screening on breast cancer mortality in women aged younger than 50 years compared with older women. Various possible reasons have been suggested for this, but none firmly is established. METHODS The Swedish Two-County Study is a randomized trial of breast cancer screening of women(More)
BACKGROUND The availability of breast carcinoma data from trials of mammographic screening provides an opportunity to study the natural history of breast carcinoma. METHODS The Swedish Two-County study is a randomized, controlled trial of mammographic screening for breast carcinoma in which 77,080 women were randomized to receive an invitation to(More)
A case-control study of cancer of the gingiva was carried out in Kerala, Southern India, using 187 cases and 895 hospital-based controls. We investigated the effects on risk in males of pan (betel)-tobacco chewing, bidi and cigarette smoking, drinking alcohol and taking snuff. In females only pan-tobacco chewing was investigated as very few females indulged(More)
A case-control study of cancer of the oral tongue and floor of mouth was conducted in Kerala, Southern India, on 228 cases and 453 hospital-based controls, matched for age, sex and religion. We studied pan(betel)-tobacco-chewing, bidi (local type of cigarette)-and-cigarette-smoking, alcohol-drinking and snuff use, for their associations with risk, in males.(More)
STUDY OBJECTIVE The aim was to investigate risk factors for cancer of the buccal and labial mucosa in Kerala, southern India. DESIGN The investigation was a case-control study. SETTING Regional Cancer Centre, Trivandrum, Kerala, and local teaching hospitals. PARTICIPANTS Cases were all those registered with oral cancers at the Regional Cancer Centre(More)
BACKGROUND Breast cancer is the most commonly occurring cancer among women in Singapore, a country which has experienced significant changes in lifestyle over the past three decades. The increase in incidence of the disease is a matter of some concern. METHODS Data from the population-based Singapore Cancer Registry for 1968-1992 were used to determine(More)
It is suspected that diet influences the risk of getting breast cancer. A study of diet and breast cancer was done among 200 Singapore Chinese women with histologically confirmed disease and 420 matched controls. A quantitative food-frequency questionnaire was used to assess intakes of selected nutrients and foods 1 year before interview. Daily intakes were(More)