S. Vimala Devi

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A protocol has been developed for in vitro clonal propagation leading to conservation of Bacopa monnieri (L) Wettst, a medicinal plant of high commercial potential with legendary reputation as a memory vitalizer. Single node explants when cultured on Murashige and Skoog’s medium supplemented with BA (0.2 mg l-1), showed active shoot proliferation (22.2(More)
Shoot multiplication of Curculigo orchioides Gaertn (Kali Musali), a threatened medicinal herb, was achieved using shoot bud explants. Single explants cultured on MS + 0.2 mg l−1 BA + 2.5 mg l−1 spermidine produced multiple shoots with an average of 7 shoots per explant that readily rooted on the same medium. Plantlets were acclimatized before successful(More)
Single dose (1 mg/rat) administration of VACOR (N-3-pyridyl methyl-N'-nitrophenyl urea) produced significant paralytic symptoms in rats. Such rats which lived for one week were sacrificed and serum AChE was extracted and purified by Sephadex column chromatography. The serum enzyme from the normal rats showed the existence of two isozymes on polyacrylamide(More)
A method is described for the extraction of mycolic acid from lepromatous leprosy tissues and from tuberculous tissues and its identification by thin layer chromatography. Verification of the mycolic acid extracted and separated by thin layer chromatography was accomplished by infrared spectroscopy. Although the presence of mycolic acid in tissues is not,(More)
Nanoenabled drug carriers are emerging as alternatives to conventional small-molecule drugs and their in-vitro biocompatibility evaluation with blood components is a necessary part of early preclinical development. In the present study, Chitosan-based bionanocomposites of sol-gel derived TiO2 and SiO2 were synthesised by the ex situ process. Samples were(More)
Applications of nanoparticles as drug delivery systems for anticancer therapeutics have great potential to revolutionize the future of cancer therapy. In the present study, Fe<sub>3</sub>O<sub>4</sub> nanoparticles were synthesized by co-precipitation method in the alkaline pH medium. The synthesized nanoparticles were characterized by X- ray diffraction(More)
Colon targeted tablet formulation was developed using okra polysaccharide (Abelmuschus esculentus) as a microbially triggered material and also as the carrier. Okra polysaccharide was isolated from Abelmuschus esculentus and used for tablet formulation with Ibuprofen as model drug. The matrix tablets with four different proportions of the okra (20%, 30%,(More)
Applications of nanoparticles as drug delivery systems for anticancer therapeutics have great potential to revolutionize the future of cancer therapy. In the present study, Fe3O4 nanoparticles were synthesized by co-precipitation method in the alkaline pH medium. The synthesized nanoparticles were characterized by X-ray diffraction and high resolution(More)
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