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In this paper, we address the problem of the efficient exploration of the architectural design space for parameterized systems. Since the design space is multi-objective, our aim is to find all the Pareto-optimal configurations that represent the best design trade-offs by varying the architectural parameters of the target system. In particular, the paper(More)
An UHPLC-MS/MS multiresidue method based on an on-line solid phase extraction (SPE) procedure was developed for the simultaneous determination of 9 perfluorinated carboxylates (from 4 to 12 carbon atoms) and 3 perfluorinated sulphonates (from 4 to 8 carbon atoms). This work proposes using an on-line solid phase extraction before chromatographic separation(More)
The Modelflow method (MM) requires the recording of the aortic pressure signal, to compute cardiac output (CO) by simulating a non-linear three-element model of aortic input impedance. We propose an extended MM to be applied to the intraventricular pressure signal, to obtain an independent estimation of CO in the setting of conductance measurements.(More)
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