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The biophysical properties of small conductance Ca(2+)-activated K(+) (SK) channels are well suited to underlie afterhyperpolarizations (AHPs) shaping the firing patterns of a conspicuous number of central and peripheral neurons. We have identified a new scorpion toxin (tamapin) that binds to SK channels with high affinity and inhibits SK channel-mediated(More)
We have characterized tamulustoxin, a novel 35-amino-acid peptide found in the venom of the Indian red scorpion (Mesobuthus tamulus). Tamulustoxin was identified through a [125I]toxin I screen, designed to identify toxins that block voltage-activated potassium channels. Tamulustoxin has also been cloned by RT-PCR, using RNA extracted from scorpion venom(More)
Two characters, “Penicillin resistance” and “fructose utilizing ability”, were transferred in the recipient Rhizobium cowpea (source—Ground nut roots) with the help of the DNA extracted from Rhizobium phaseoli culture (source—French bean roots). The recipient culture enters the logarithmic growth phase at the end of 60 min. The percentage transformation(More)
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