S. Traverso

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Opening of CLC chloride channels is coupled to the translocation of the permeant anion. From the recent structure determination of bacterial CLC proteins in the closed and open configuration, a glutamate residue was hypothesized to form part of the Cl--sensitive gate. The negatively charged side-chain of the glutamate was suggested to occlude the permeation(More)
CLC Cl- channels are homodimers in which each subunit has a proper pore and a (fast) gate. An additional slow gate acts on both pores. A conserved glutamate (E166 in CLC-0) is a major determinant of gating in CLC-0 and is crucially involved in Cl-/H+ antiport of CLC-ec1, a CLC of known structure. We constructed tandem dimers with one wild-type (WT) and one(More)
CLC proteins are a nine-member gene family of Cl- channels that have diverse roles in the plasma membrane and in intracellular organelles. The recent structure determination of bacterial CLC homologues by Dutzler et al. was a breakthrough for the structure-function analysis of CLC channels. This review describes the mechanisms of inhibition of muscle type(More)
In this paper, we propose a new channel equalization using frequency and/or time spreading for UWB multiband OFDM schemes. The proposed equalizer is optimal in the least square sense, and does not increase complexity compared to classical equalizers. The performance of this equalizer is studied for channel delay spread below the guard interval
In addition to the power nonlinearity, the high frequency (HF) memory effects of the power amplifier (PA) have a distorting influence even in the linear zone. The objective of this paper is to present a simple way to compensate for these memory effects in an orthogonal frequency division multiplex (OFDM) system. In order to represent the PA with HF memory(More)
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