S. Sivasankar

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Direct measurements of the interactions between antiparallel, oriented monolayers of the complete extracellular region of C-cadherin demonstrate that, rather than binding in a single unique orientation, the cadherins adhere in three distinct alignments. The strongest adhesion is observed when the opposing extracellular fragments are completely(More)
In this work, we used direct measurements with the surface force apparatus to determine the pH-dependent electrostatic charge density of a single binding face of streptavidin. Mean field calculations have been used with considerable success to model electrostatic potential fields near protein surfaces, but these models and their inherent assumptions have(More)
— The basic concept discussed here is the use of wireless media to replace the use of ire wired media to transmit the power. The world is advancing so the usage of wireless power came into existence. Experiments are going on so that the usage of power can be done through all the home appliances there by reducing the usage of wired technologies. For example,(More)
under the Creative Commons Attribution License, which permits unrestricted use, distribution , and reproduction in any medium, provided the original work is properly cited. Abstract In this paper, we introduce the notion of balanced intuitionistic fuzzy graphs and present some of their properties. We also prove that G 1 G 2 is balanced if and only if D(G 1)(More)
Cadherins are Ca(2+)-dependent cell-cell adhesion proteins that maintain the structural integrity of the epidermis; their principle function is to resist mechanical force. This review summarizes the biophysical mechanisms by which classical cadherins tune adhesion and withstand mechanical stress. We first relate the structure of classical cadherins to their(More)
Prion protein (PrP) misfolding and oligomerization are key pathogenic events in prion disease. Copper exposure has been linked to prion pathogenesis; however, its mechanistic basis is unknown. We resolve, with single-molecule precision, the molecular mechanism of Cu(2+)-induced misfolding of PrP under physiological conditions. We also demonstrate that(More)