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OBJECTIVE To investigate the associations between Parkinson's disease and other degenerative parkinsonian syndromes and environmental factors in five European countries. METHODS A case-control study of 959 prevalent cases of parkinsonism (767 with Parkinson's disease) and 1989 controls in Scotland, Italy, Sweden, Romania and Malta was carried out. Cases(More)
BACKGROUND Air pollution from biomass fuels in Africa is a significant cause of mortality and morbidity both in adults and children. The work describes the nature and quantity of smoke exposure from biomass fuel in Malawian homes. METHODS Markers of indoor air quality were measured in 62 homes (31 rural and 31 urban) over a typical 24 h period. Four(More)
The exposure of children to air pollution in low resource settings is believed to be high because of the common use of biomass fuels for cooking. We used microenvironment sampling to estimate the respirable fraction of air pollution (particles with median diameter less than 4 μm) to which 7-9 year old children in southern Nepal were exposed. Sampling was(More)
Improvements in short-axis blood-myocardium contrast in the heart with the use of four magnetization preparation schemes applied before the imaging sequence are demonstrated. Gradient-echo cine cardiac images are acquired and compared at 0.95 T incorporating T2, T1rho, magnetization transfer, and double inversion (black blood) preparations in a series of(More)
AIMS To determine whether acquired colour vision deficits in solvent exposed individuals are associated with cognitive impairment. METHODS A sample of 82 painters and 38 other subjects were studied. Alcohol, drug, and smoking histories were obtained. Colour vision was tested using the Lanthony D-15-d colour vision test. Cognitive impairment was measured(More)
paper presents the work carried out in developing a precision, bolus injection system to study the effect of regional deposition of fine particulate matter (PM) within the human respiratory system and to investigate the optimal conditions for inhaled drug delivery. In contrast to existing methods, the new system computes parameters necessary and injects PM(More)
Background. Since the escalation of the outbreak of Ebola virus disease (Ebola) in August 2014, the New Jersey Department of Health (NJDOH) has provided guidance to clinicians on the management of persons under investigation (PUIs) for Ebola. On October 27, 2014, the Centers for Disease Control and Prevention instituted a policy of active monitoring (AM),(More)
Multi-parametric MR image registration combines different imaging sequences to enhance visualisation and analysis. However, alignment of the different acquisitions is challenging , due to contrast-dependent anatomical information and abundant artefacts. For two decades, voxel-based registration has been dominated by methods based on mutual information,(More)
precision, bolus injection system to study the effect of regional deposition of fine particulate matter (PM) within the human respiratory system and to investigate the optimal conditions for inhaled drug delivery. In contrast to existing methods, the new system computes parameters necessary and injects PM into breath cycles by a process of dynamic breath(More)
A novel T*(2)-weighted contrast-preparation scheme is described for use with segmented k-space cardiac sequences. This approach frees the imaging phase from the requirement of a long TE and, hence, a relatively long TR. A [90 degrees (x)-tau-90 degrees (rho)] preparation scheme is used to acquire four image data sets with the phase rho of the second pulse(More)
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