S. Satyanarayana

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Three new mononuclear [Ru (phen)2 ptip](2+) (1), [Ru (bpy)2 ptip](2+) (2) and [Ru (dmb)2 ptip](2+) (3) [ptip=(2-(5-phenylthiophen-2-yl)-1H-imidazo[4, 5-f][1,10 phenanthroline, phen=1, 10 phenanthroline, bpy=2, 2' bipyridine, dmb=4, 4'-dimethyl 2, 2' bipyridine] complexes were synthesized and characterised by elemental analysis, IR, NMR and Mass spectra. The(More)
In an endeavor toward the development of metal-based anticancer drugs, we present here the design, synthesis and characterization of three ruthenium(II) functionalized phenanthroline complexes with extended π-conjugation. These complexes have been shown to act as promising CT-DNA intercalators as evidenced by UV-visible, luminescence, emission quenching by(More)
The new ligand 4-(isopropylbenzaldehyde)imidazo[4,5-f ][1,10]phenanthroline (ippip) and its complexes [Ru(phen)2(ippip)]2+(1),[Co(phen)2(ippip)]3+(2),[Ru(bpy)2(ippip)]2+(3),[Co(bpy)2(ippip)]3+(4)(bpy=2,2-bipyridine) and (phen=1,10-phenanthroline) were synthesized and characterized by ES+-MS, 1H and 13C NMR. The DNA binding properties of the four complexes(More)
In this paper, three complexes of type [Co(en)(2)PIP](3+)(PIP=2-phenylimidazo[4,5-f][1,10,] phenanthroline)(1), [Co(en)(2)IP](3+) (IP = imidazo[4,5-f][1,10,] phenanthroline)(2), and [Co(en)(2)phen-dione](3+)(1,10 phenanthroline 5,6,dione)(3) have been synthesized and characterized by UV/VIS, IR, (1)H NMR spectral methods. Absorption spectroscopy, emission(More)
Oxidative stress is involved in diabetes mellitus and its complications. Since diabetes is a stress-related disorder, supplementation with antioxidants may improve the condition. The purpose of this study is to know the effect of oral administration of selenium on blood glucose and its influence on gliclazide induced hypoglycaemia/antihyperglycaemia in(More)
The novel ligand (dmbip) 2-(4-N, N-dimethylbenzenamine)1H-imidazo[4, 5-f][1, 10]phenanthroline and its complexes [Ru(phen)2dmbip]2+ (1), [Ru(bpy)2dmbip]2+ (2), [Co(phen)2dmbip]3+ (3) and [Co(bpy)2dmbip]3+ (4) [where phen = 1, 10-phenanthroline, bpy = 2, 2′-bipyridine], have been synthesized and characterized by elemental analysis, IR, UV-Vis, 1H NMR, 13C(More)
Three Ruthenium(II) polypyridine complexes, [Ru(phen)2(mipc)]2+(1), [Ru(bpy)2(mipc)]2+ (2) and [Ru(dmb)2(mipc)]2+(3) [mipc = 2-(6-methyl-3-(1H-imidazo[4, 5-f][1,10]-phenanthroline-2-yl)-4H-chromene-4-one, phen = 1,10-phenanthroline,bpy = 2, 2′bipyridine,dmb = 4, 4′-dimethyl-2, 2′-bipyridine] have been synthesized and characterized by elemental analysis, IR,(More)
A series of mixed-ligand ruthenium(II) complexes of the type [Ru(en)(2)bpy](2+) (bpy=2,2-bipyridine; 1), [Ru(en)(2)phen](2+) (phen=1,10-phenantroline; 2), [Ru(en)(2)IP](2+) (IP=imidazo[4,5-f][1,10]phenanthroline; 3), and [Ru(en)(2)PIP](2+) (PIP=2-phenylimidazo[4,5-f][1,10]phenanthroline; 4) have been isolated and characterized by UV/VIS, IR, and (1)H-NMR(More)
A new ligand 3-(1H-imidazo[4,5-f][1,10]phenanthrolin-2yl)phenylboronic acid and its (IPPBA) three ruthenium(II) complexes [Ru(phen)2(IPPBA)](ClO4)2 (1), [Ru(bpy)2(IPPBA)](ClO4)2 (2) and [Ru(dmb)2(IPPBA)](ClO4)2 (3) have been synthesized and characterized by elemental analysis, UV/VIS, IR, 1H-NMR,13C-NMR and mass spectra. The binding behaviors of the three(More)
Three new ruthenium(II) polypyridyl complexes [Ru(phen)2BrIPC](2+) (1), [Ru(bpy)2 BrIPC](2+) (2) and [Ru(dmb)2BrIPC](2+) (3) where, BrIPC = (6-bromo-3-(1H-imidazo[4,5-f] [1,10]-phenanthroline, phen = 1,10-phenanthroline, bpy = 2,2' bipyridine, dmb = 4,4'-dimethyl 2,2' bipyridine, were synthesised and characterised. DNA-binding nature was investigated by(More)