Learn More
Peptoids differ from peptides in that peptoids are composed of N-substituted rather than alpha-carbon-substituted glycine units. In this paper we report the in vitro and in vivo antibacterial activities of several antibacterial peptoids discovered by screening combinatorial chemistry libraries for bacterial growth inhibition. In vitro, the peptoid CHIR29498(More)
N-alkylated glycine trimers are generically referred to as peptoids. The identification of antimicrobial peptoids from a statistically unbiased diverse combinatorial chemistry library led to the design of the optimization peptoid library that we describe in this manuscript. This optimization library was designed using structural information from the most(More)
This paper presents the corrosion behaviour of welded low carbon steel at different welding voltages and filler materials. The welding process was conducted on butt joint specimens using the metal inert gas (MIG) technique at a welding voltage range of 19 to 21 V with 1 V interval, and the filler materials used were ER 308L and ER 70S-6 with 1.2 mm(More)
The PI3K/AKT/mTOR pathway is frequently activated in head and neck squamous cell carcinoma (HNSCC), but pathway inhibition has variable efficacy. Identification of predictive biomarkers and mechanisms of resistancewould allow selection of patientsmost likely to respond andnovel therapeutic combinations. The purpose of this study was to extend recent(More)
  • 1