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Summary form only given. A fast algorithm for solving a large system with an essentially Toeplitz five-band coefficient matrix is presented. The first two and last two rows are influenced by boundary conditions. The five band core of this matrix is factored as the product of tridiagonal matrices for the purpose of obtaining a solution of a linear system(More)
Gaucher disease (GD) is the most common lysosomal storage disorder, caused by deficiency of acid beta glucosidase. GD usually presents in children but occasional cases can present in adulthood. Here we report a case of type I GD in a 37 year old female who presented with intracerebral bleed due to long standing thrombocytopenia. She underwent splenectomy in(More)
Chemotherapy drug resistance and relapse of the disease have been the major factors limiting the success of acute myeloid leukemia (AML) therapy. Several factors, including the pharmacokinetics (PK) of Cytarabine (Ara-C) and Daunorubicin (Dnr), could contribute to difference in treatment outcome in AML. In the present study, we evaluated the plasma PK of(More)
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