S. S. Maxwell

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OBJECTIVE We performed a systematic review and meta-analyses to assess the evidence for genetic associations with brain microbleeds (BMBs). METHODS We sought all published studies of the association between any genetic polymorphism and BMBs studied in a total of >100 people. We critically appraised studies, and calculated pooled odds ratios (ORs) using(More)
1. The dogfish responds to certain contact stimuli by definite stereotropic reactions. These reactions can be positive or negative. 2. The sense of the stereotropic response depends on the strength of the stimulus; a "weak" stimulus, produces a positive and a "strong" stimulus, a negative response. 3. The strength of stimulus necessary to cause a reversal(More)
It has long been known that the eye movements resulting from the stimulation of any ampulla correspond very closely to the compensatory movements brought about by rotation of the animal in the plane of the semicircular canal of which that ampulla forms a part. In the dogfish this correspondence has been shown by the work of Lee (1894) and of one of us(More)
It It has been pointed out by Loeb 1 that our orientation in space is determined mainly by three groups of tropistic influences; namely, light, gravitation, and contact. Light and gravitation cause the orientation of organisms through effects upon muscle tonus. When the lines of force strike the animal obliquely, as for example, when light rays fall(More)
1. A dogfish from which all six ampullae have been removed maintains its equilibrium; the righting reactions occur promptly; compensatory movements of the eyes occur in response to rotations in all planes except the horizontal; the compensatory position of the eyes is retained if the animal is held in an abnormal position. Both the static and dynamic(More)
1. The reflex effect of direct mechanical stimulation of the exposed ampulla of the horizontal canal has been graphically recorded for each of the six extrinsic muscles of the eyeball. 2. Stimulation of a horizontal ampulla evokes a strong contraction of the homolateral rectus internus and of the contralateral rectus externus; at the same time the(More)